PADB-logoLSSR - molecule cluster A8688BCL10-interacting CARD protein

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensBINCA_HUMANQ96LW722825589 

Functions and Classifications

GOC:cytosol, C:endoplasmic reticulum membrane, C:integral component of membrane, C:mitochondrial membrane, C:nucleus, F:CARD domain binding, P:negative regulation of I-kappaB kinase/NF-kappaB signaling, P:negative regulation of I-kappaB kinase/NF-kappaB cascade
UniProt3D-structure, Alternative splicing, Complete proteome, Disulfide bond, Endoplasmic reticulum, Membrane, Mitochondrion, Nucleus, Reference proteome, Transmembrane, Transmembrane helix, Phosphoprotein
PADBTM: transmembrane

Expression

percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
00366005163239218

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
16899541ratkidneyinner medullary collecting duct (IMCD) Perfusion-biotinylation or incubation-biotinylation of IMCD     

Compile date 12-23-2014© PADB initiative