PADB-logoLSSR - molecule cluster A8400CSTB, CST6, STFBCystatin B

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensCYTB_HUMANP040809811140254800, 601145

Functions and Classifications

GOC:cytoplasm, C:nucleolus, F:cysteine-type endopeptidase inhibitor activity, P:adult locomotory behavior, P:regulation of apoptotic process, P:negative regulation of endopeptidase activity
UniProt3D-structure, Acetylation, Complete proteome, Cytoplasm, Direct protein sequencing, Disease mutation, Epilepsy, Nucleus, Protease inhibitor, Reference proteome, Thiol protease inhibitor
PADBINH: inhibitor (protease, kinase, other enzymes, pathways)

Expression

percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
6011110000617001139

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16948836humanurinewhole healthy     
18501002mousekidneycortexCytoplasmhealthy     
16684767humanbloodplasma severe trauma     Identified peptides: 2
16901338humantearwhole healthy     
16446289humanhairshaft healthy     
18361515humansalivaParotid;SMSL healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
21616181mousecornea  lumican knock-out   0.955 
17123452humankidneywhole renal cell carcinoma  up4 +/- 1 
16449382ratkidneyinner medullary collecting duct (IMCD) Flow through proteins from avidin affinity step of technique 4     
15951573humanlungbronchoalveolar lavage asthma     
15048992humansalivawhole healthy      
15473691humansalivawhole healthy     Unique peptides: 25
15492834humansalivasubmandibular (SM) secretion healthy      
15723531humansalivaparotid healthy     
15800970humansalivawhole healthy     
16402355humansalivawhole healthy      
16440601humansalivawhole healthy     
16440601humansalivawhole healthy     
16440601humansalivawhole healthy     
16739998humansalivawhole healthy     
15064947humantestiswhole healthy     
15140760humanurinewhole Dent's disease   >1 Identified peptides: 1
21127740humanurinewhole acute abdominal pain     Identified peptides: 37
UNPUBLISHED_1humanurinewhole cancer     
18578523humanPC3 cancer cellsecretion       
23376485humanurinepodocyte healthy     
23376485humanurinepodocyte healthy     
UNPUBLISHED_3humanPC3 cancer cellwhole        
18553995humanprostatewhole prostate cancer     Identified peptides: 4
20334419humanprostateprostate secretion healthy     
19056867humanurineexosome healthy     Identified peptides: 2

Compile date 12-23-2014© PADB initiative