PADB-logoLSSR - molecule cluster A8077TXNDC17, TXNL5Thioredoxin domain-containing protein 17

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensTXD17_HUMANQ9BRA212313941 

Functions and Classifications

GOC:cytosol, F:electron carrier activity, F:peroxidase activity, F:protein-disulfide reductase activity, P:tumor necrosis factor-mediated signaling pathway
UniProt3D-structure, Acetylation, Complete proteome, Cytoplasm, Direct protein sequencing, Disulfide bond, Redox-active center, Reference proteome
PADBUK: unknown

Expression

percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
88808000003801515

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16948836humanurinewhole healthy     
16948836humanurinewhole healthy     
18501002mousekidneycortexCytoplasmhealthy     
16684767humanbloodplasma severe trauma     Identified peptides: 1
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
21616181mousecornea  lumican knock-out   1.96 
16449382ratkidneyinner medullary collecting duct (IMCD) Flow through proteins from avidin affinity step of technique 4     
17711322humankidneyglomerulus healthy     
15951573humanlungbronchoalveolar lavage asthma     
21127740humanurinewhole acute abdominal pain     Identified peptides: 12
UNPUBLISHED_1humanurinewhole cancer     
18578523humanPC3 cancer cellsecretion       
18578523humanPC3 cancer cellsecretion       
23376485humanurinepodocyte healthy     
UNPUBLISHED_3humanPC3 cancer cellwhole        
18553995humanprostatewhole prostate cancer     Identified peptides: 2
19056867humanurineexosome healthy     Identified peptides: 2

Compile date 12-23-2014© PADB initiative