PADB-logoLSSR - molecule cluster A7981THOP1Thimet oligopeptidase 1

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensTHOP1_HUMANP5288868978840601117

Functions and Classifications

GOC:cytoplasm, F:metal ion binding, F:metalloendopeptidase activity, F:peptide binding, P:peptide metabolic process, P:proteolysis, P:intracellular protein kinase cascade
UniProt3D-structure, Acetylation, Complete proteome, Cytoplasm, Direct protein sequencing, Hydrolase, Metal-binding, Metalloprotease, Phosphoprotein, Protease, Reference proteome, Zinc
PADBENZ: enzyme, enzymatic properties

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16684767humanbloodplasma severe trauma     Identified peptides: 2
21616181mousecornea  lumican knock-out   1.07 
16861337humanblooderythrocytecytoplasmichealthy     
16449382ratkidneyinner medullary collecting duct (IMCD) Flow through proteins from avidin affinity step of technique 4     
18582094mousetestiswhole healthy     

Compile date 12-23-2014© PADB initiative