PADB-logoLSSR - molecule cluster A7931RARSArginyl-tRNA synthetase

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensSYRC_HUMANP5413666075379107820

Functions and Classifications

GOC:aminoacyl-tRNA synthetase multienzyme complex, C:cytosol, C:mitochondrion, C:nucleus, F:arginine binding, F:arginine-tRNA ligase activity, F:ATP binding, F:tRNA binding, P:arginyl-tRNA aminoacylation, C:cytoplasm
UniProtAcetylation, Alternative initiation, Aminoacyl-tRNA synthetase, ATP-binding, Complete proteome, Cytoplasm, Direct protein sequencing, Ligase, Nucleotide-binding, Polymorphism, Protein biosynthesis, Reference proteome
PADBENZ: enzyme, enzymatic properties

Expression

ratios [in mouse]
cytosol/nucleusheart/brainkidney/brainliver/brain
12   
percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
0000000000100000

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
18501002mousekidneycortexCytoplasmhealthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
21616181mousecornea  lumican knock-out   1.255 
21170055humanbrainPSD (neocortex) Glial neoplasm/Lesional epilepsy/Colloid cyst     Unique peptides: 3
16899541ratkidneyinner medullary collecting duct (IMCD) Perfusion-biotinylation or incubation-biotinylation of IMCD     
17711322humankidneyglomerulus healthy     
16615899mouseliverorganelleCytosol (Cyto)healthy     
21127740humanurinewhole acute abdominal pain     Identified peptides: 2
23308193humanbladder cancer cell linecytosolic and nuclear fractionation bladder cancer   1.59 
23376485humanurinepodocyte healthy     
UNPUBLISHED_2humanliverwhole, fetal healthy     
UNPUBLISHED_2humanliverwhole, fetal healthy     
UNPUBLISHED_2humanliverwhole, fetal healthy     
UNPUBLISHED_3humanPC3 cancer cellwhole        
19056867humanurineexosome healthy     Identified peptides: 1

Compile date 12-23-2014© PADB initiative