PADB-logoLSSR - molecule cluster A7927NARSAsparaginyl-tRNA synthetase, cytoplasmic

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensSYNC_HUMANO4377654862943108410

Functions and Classifications

GOC:cytosol, C:mitochondrion, F:asparagine-tRNA ligase activity, F:ATP binding, F:nucleic acid binding, P:asparaginyl-tRNA aminoacylation, P:tRNA aminoacylation for protein translation, C:cytoplasm
UniProtAcetylation, Aminoacyl-tRNA synthetase, ATP-binding, Complete proteome, Cytoplasm, Direct protein sequencing, Ligase, Nucleotide-binding, Phosphoprotein, Protein biosynthesis, Reference proteome
PADBENZ: enzyme, enzymatic properties

Expression

ratios [in mouse]
cytosol/nucleusheart/brainkidney/brainliver/brain
18   
percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
00330000000330033

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
18501002mousekidneycortexCytoplasmhealthy     
16684767humanbloodplasma severe trauma     Identified peptides: 1
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
21616181mousecornea  lumican knock-out   1.145 
17711322humankidneyglomerulus healthy     
16615899mouseliverorganelleCytosol (Cyto)healthy     
21127740humanurinewhole acute abdominal pain     Identified peptides: 6
23308193humanbladder cancer cell linecytosolic and nuclear fractionation bladder cancer   1.8 
UNPUBLISHED_2sheepbrainfrontal cortex healthy     
UNPUBLISHED_3humanPC3 cancer cellwhole        
20334419humanprostateprostate secretion healthy     
19056867humanurineexosome healthy     Identified peptides: 1

Compile date 12-23-2014© PADB initiative