PADB-logoLSSR - molecule cluster A7482PPM1B, PP2CBProtein phosphatase 1B

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensPPM1B_HUMANO7568847952643603770

Functions and Classifications

GOC:cytosol, C:membrane, F:magnesium ion binding, F:manganese ion binding, F:protein serine/threonine phosphatase activity, P:cytokine-mediated signaling pathway, P:N-terminal protein myristoylation, P:negative regulation of defense response to virus, P:negative regulation of I-kappaB kinase/NF-kappaB signaling, P:negative regulation of interferon-beta production, P:negative regulation of NF-kappaB import into nucleus, P:peptidyl-threonine dephosphorylation, P:protein dephosphorylation, F:phosphoprotein phosphatase activity, P:dephosphorylation, P:metabolic process
UniProt3D-structure, Alternative splicing, Complete proteome, Cytoplasm, Hydrolase, Isopeptide bond, Lipoprotein, Magnesium, Manganese, Membrane, Metal-binding, Myristate, Protein phosphatase, Reference proteome, Ubl conjugation
PADBENZ: enzyme, enzymatic properties

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
18501002mousekidneycortexUnknownhealthy     
21616181mousecornea  lumican knock-out   1.09 
15800970humansalivawhole healthy     

Compile date 12-23-2014© PADB initiative