PADB-logoLSSR - molecule cluster A7266PLA2G4B, CPLA2 BETACytosolic phospholipase A2 beta

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensPA24B_HUMANP0C86978187978606088

Functions and Classifications

GOC:cytosol, C:early endosome membrane, C:extracellular region, C:mitochondrial inner membrane, F:calcium ion binding, F:calcium-dependent phospholipase A2 activity, F:calcium-dependent phospholipid binding, F:lysophospholipase activity, P:activation of signaling protein activity involved in unfolded protein response, P:arachidonic acid metabolic process, P:calcium-mediated signaling, P:cellular protein metabolic process, P:glycerophospholipid catabolic process, P:inflammatory response, P:parturition, P:phosphatidic acid biosynthetic process, P:phosphatidylcholine acyl-chain remodeling, P:phosphatidylethanolamine acyl-chain remodeling, P:phosphatidylglycerol acyl-chain remodeling, P:phosphatidylserine acyl-chain remodeling
UniProtAlternative splicing, Calcium, Complete proteome, Cytoplasm, Endosome, Hydrolase, Lipid degradation, Lipid metabolism, Membrane, Metal-binding, Mitochondrion, Polymorphism, Reference proteome
PADBENZ: enzyme, enzymatic properties

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
21616181mousecornea  lumican knock-out   0.935 

Compile date 12-23-2014© PADB initiative