PADB-logoLSSR - molecule cluster A6831GCAT, KBL2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial precursor

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensKBL_HUMANO7560041945285607422

Functions and Classifications

GOC:mitochondrion, C:nucleus, F:glycine C-acetyltransferase activity, F:pyridoxal phosphate binding, P:biosynthetic process, P:cellular amino acid metabolic process, P:L-threonine catabolic process to glycine, F:catalytic activity, F:ligase activity, F:transferase activity
UniProtAcetylation, Acyltransferase, Alternative splicing, Complete proteome, Mitochondrion, Nucleus, Polymorphism, Pyridoxal phosphate, Reference proteome, Transferase, Transit peptide, Ligase
PADBENZ: enzyme, enzymatic properties

Expression

ratios [in rat]
cytosol/nucleusheart/brainkidney/brainliver/brain
 0.941.091.19
percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
114061500310178925

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
18501002mousekidneycortexCytoplasmhealthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
21616181mousecornea  lumican knock-out   0.98 
17172703humanmultiplemitochondriaMitochondrialhealthy     detection: high confidence prediction (Mitopred)confidence %: 99
16928776ratbrain;heart;kidney;livermitochondria healthy      
16615899mouseliverorganelleMitochondrion (Mito)healthy     

Compile date 12-23-2014© PADB initiative