PADB-logoLSSR - molecule cluster A626ANovel protein similar to REV3L (yeast homolog-like), catalytic subunit of DNA polymerase zeta POLZ

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensK2022_HUMANQ5QGS01516167551300524

Functions and Classifications

GOC:delta DNA polymerase complex, F:3'-5' exonuclease activity, F:DNA-directed DNA polymerase activity, P:base-excision repair, gap-filling, P:DNA replication proofreading, P:DNA replication, removal of RNA primer, P:nucleotide-excision repair, DNA gap filling, P:regulation of mitotic cell cycle, P:regulation of mitotic cell cycle, P:S phase of mitotic cell cycle"
UniProtChromosomal rearrangement, Complete proteome, Polymorphism, Reference proteome
PADBTF: transcription and translation, gene regulation

Expression

percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
00025050000025000

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16684767humanbloodplasma severe trauma     Identified peptides: 1
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     

Compile date 12-23-2014© PADB initiative