PADB-logoLSSR - molecule cluster A594CTCN2, TC2Transcobalamin-2

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensTCO2_HUMANP2006242747450275350, 613441

Functions and Classifications

GOC:endosome, C:extracellular space, C:lysosomal lumen, F:cobalamin binding, F:metal ion binding, P:cobalamin metabolic process, P:cobalamin transport, P:cobalt ion transport
UniProt3D-structure, Alternative splicing, Cobalt, Cobalt transport, Complete proteome, Direct protein sequencing, Disulfide bond, Ion transport, Metal-binding, Polymorphism, Reference proteome, Secreted, Signal, Transport
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Expression

percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
00001800000001864

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16948836humanurinewhole healthy     
18501002mousekidneycortexExtracellular Spacehealthy     
16684767humanbloodplasma severe trauma     Identified peptides: 1
16901338humantearwhole healthy     
18361515humansalivaParotid healthy     Identified peptides: 4
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
21616181mousecornea  lumican knock-out   1.22 
21127740humanurinewhole acute abdominal pain     Identified peptides: 1
23376485humanurinepodocyte healthy     

Compile date 12-23-2014© PADB initiative