PADB-logoLSSR - molecule cluster A5824AKR7A2, AFAR, AFAR1Aflatoxin B1 aldehyde reductase 1

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensARK72_HUMANO4348835939589603418

Functions and Classifications

GOC:Golgi apparatus, F:alditol:NADP+ 1-oxidoreductase activity, F:electron carrier activity, F:phenanthrene-9,10-epoxide hydrolase activity, P:carbohydrate metabolic process, P:cellular aldehyde metabolic process, P:daunorubicin metabolic process, P:doxorubicin metabolic process
UniProt3D-structure, Acetylation, Complete proteome, Cytoplasm, Direct protein sequencing, Golgi apparatus, NADP, Oxidoreductase, Polymorphism, Reference proteome, Phosphoprotein
PADBENZ: enzyme, enzymatic properties

Expression

ratios [in mouse, rat]
cytosol/nucleusheart/brainkidney/brainliver/brain
7.30.640.70.64
percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
332423172353611810

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16948836humanurinewhole healthy     
18501002mousekidneycortexCytoplasmhealthy     
16684767humanbloodplasma severe trauma     Identified peptides: 3
16709260humansemenplasma healthy     
16901338humantearwhole healthy     
16446289humanhairshaft healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
21616181mousecornea  lumican knock-out   1.26 
21170055humanbrainPSD (neocortex) Glial neoplasm/Lesional epilepsy/Colloid cyst     Unique peptides: 4
16928776ratbrain;heart;kidney;livermitochondria healthy      
16449382ratkidneyinner medullary collecting duct (IMCD) Flow through proteins from avidin affinity step of technique 4     
17711322humankidneyglomerulus healthy     
16691549ratliverGolgi healthy      
16615899mouseliverorganellePlasma membrane (PM)|Cytosol (Cyto)healthy     
15951573humanlungbronchoalveolar lavage asthma     
16021519humanovarywhole healthy     
15064947humantestiswhole healthy     
18582094mousetestiswhole healthy     
21127740humanurinewhole acute abdominal pain     Identified peptides: 29
UNPUBLISHED_1humanurinewhole cancer     
18578523humanPC3 cancer cellsecretion       
23376485humanurinepodocyte healthy     
UNPUBLISHED_2sheepbrainfrontal cortex healthy     
UNPUBLISHED_2sheepbrainfrontal cortex healthy     
UNPUBLISHED_2sheepbrainhippocampus healthy     
UNPUBLISHED_2humanliverwhole, fetal healthy     
UNPUBLISHED_2humanliverwhole, fetal healthy     
UNPUBLISHED_3humanPC3 cancer cellwhole        
20334419humanprostateprostate secretion healthy     
19056867humanurineexosome healthy     Identified peptides: 2

Compile date 12-23-2014© PADB initiative