PADB-logoLSSR - molecule cluster A555BOSTC, DC2, HDCMD45POligosaccharyltransferase complex subunit OSTC

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensOSTC_HUMANQ9NRP014916829 

Functions and Classifications

GOC:integral component of membrane, C:oligosaccharyltransferase complex, P:protein N-linked glycosylation via asparagine, C:integral to membrane
UniProtAlternative splicing, Complete proteome, Membrane, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix
PADBTM: transmembrane

Expression

percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
00000500000001338

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
21616181mousecornea  lumican knock-out   0.89 
17172703humanmultiplemitochondriaMitochondrialhealthy     detection: high confidence prediction (Mitopred)confidence %: 99
17627911ratbloodserum bone loss model (associated with extended bed rest or space travel) by Hindlimb unloading  downregulated   
15905145ratkidneyinner medullary collecting duct (IMCD) Isolation of AQP-2 containing intracellular vesicles     
16691549ratliverGolgi healthy      
16691549ratliverGolgi healthy      
15684408mouseplasma membranebrain cortex and hippocampus healthy     
UNPUBLISHED_3humanPC3 cancer cellwhole        

Compile date 12-23-2014© PADB initiative