PADB-logoLSSR - molecule cluster A527CSNX6Sorting nexin 6

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensSNX6_HUMANQ9UNH740646649606098

Functions and Classifications

GOC:cytoplasmic vesicle membrane, C:early endosome membrane, C:nucleus, F:phosphatidylinositol binding, P:cell communication, P:intracellular protein transport, P:negative regulation of epidermal growth factor-activated receptor activity, P:negative regulation of transcription, DNA-templated, P:negative regulation of transforming growth factor beta receptor signaling pathway, P:retrograde transport, endosome to Golgi, C:intracellular membrane-bounded organelle, P:negative regulation of transcription, DNA-dependent
UniProtAcetylation, Alternative splicing, Complete proteome, Cytoplasm, Cytoplasmic vesicle, Endosome, Lipid-binding, Membrane, Nucleus, Protein transport, Reference proteome, Transport
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
18501002mousekidneycortexCytoplasmhealthy     
21616181mousecornea  lumican knock-out   1.23 
21170055humanbrainPSD (neocortex) Glial neoplasm/Lesional epilepsy/Colloid cyst     Unique peptides: 2
16691549ratliverGolgi healthy      
18582094mousetestiswhole healthy     
15064947humantestiswhole healthy     
23308193humanbladder cancer cell linecytosolic and nuclear fractionation bladder cancer   1.09 

Compile date 12-23-2014© PADB initiative