PADB-logoLSSR - molecule cluster A524AHDGF, HMG1L2Hepatoma-derived growth factor

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensHDGF_HUMANP5185824026788600339, 300043

Functions and Classifications

GOC:cytoplasm, C:extracellular space, C:transcriptional repressor complex, F:DNA binding, F:heparin binding, F:nucleotide binding, F:RNA polymerase II transcription corepressor activity, P:activation of signaling protein activity involved in unfolded protein response, P:cell proliferation, P:cellular protein metabolic process
UniProt3D-structure, Acetylation, Alternative splicing, Complete proteome, Cytoplasm, Direct protein sequencing, DNA-binding, Growth factor, Heparin-binding, Isopeptide bond, Nucleotide-binding, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Repressor, Transcription, Transcription regulation, Ubl conjugation
PADBTF: transcription and translation, gene regulation

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
18501002mousekidneycortexExtracellular Spacehealthy     
21616181mousecornea  lumican knock-out   0.98 
16641100ratkidneyinner medullary collecting duct (IMCD) Phosphoproteome of IMCD     
17711322humankidneyglomerulus healthy     
17711322humankidneyglomerulus healthy     
17711322humankidneyglomerulus healthy     
15951573humanlungbronchoalveolar lavage asthma     
18578523humanPC3 cancer cellsecretion       
UNPUBLISHED_3humanPC3 cancer cellwhole        
18553995humanprostatewhole prostate cancer     Identified peptides: 4

Compile date 12-23-2014© PADB initiative