PADB-logoLSSR - molecule cluster A4752DSC3, CDHF3, DSC4Desmocollin 3 precursor

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensDSC3_HUMANQ14574896100013600271, 613102

Functions and Classifications

GOC:cell-cell junction, C:cytoplasm, C:desmosome, C:extracellular region, C:integral component of membrane, C:plasma membrane, F:calcium ion binding, P:cell adhesion, P:homophilic cell adhesion, P:in utero embryonic development, P:protein stabilization, C:integral to membrane, C:membrane
UniProtAlternative splicing, Calcium, Cell adhesion, Cell junction, Cell membrane, Cleavage on pair of basic residues, Complete proteome, Direct protein sequencing, Glycoprotein, Hypotrichosis, Membrane, Metal-binding, Polymorphism, Reference proteome, Repeat, Signal, Transmembrane, Transmembrane helix, Phosphoprotein
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16948836humanurinewhole healthy     
17723740humanurinewhole healthy     
16684767humanbloodplasma severe trauma     Identified peptides: 2
16709260humansemenplasma healthy     
16446289humanhairshaft healthy     
18361515humansalivaParotid healthy     Identified peptides: 8
21616181mousecornea  lumican knock-out   0.745 
15951573humanlungbronchoalveolar lavage asthma     
17494094humanurinewhole healthy; tubular proteinuria (TP), X-linked form of renal Fanconi syndrome; Dent's disease, X-linked form of renal Fanconi syndrome; Lowe disease, X-linked form of renal Fanconi syndrome; autosomal dominant idiopathic form (ADIF) of renal Fanconi syndrome   0.32 
21127740humanurinewhole acute abdominal pain     Identified peptides: 4
18578523humanPC3 cancer cellsecretion       
23376485humanurinepodocyte healthy     

Compile date 12-23-2014© PADB initiative