PADB-logoLSSR - molecule cluster A4642ALCAM, MEMDCD166 antigen precursor

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensCD166_HUMANQ1374058365132601662

Functions and Classifications

GOC:axon, C:external side of plasma membrane, C:extracellular region, C:integral component of membrane, C:neuronal cell body, F:receptor binding, P:axon guidance, P:cell adhesion, P:motor neuron axon guidance, P:signal transduction, C:membrane, C:integral to membrane
UniProt3D-structure, Alternative splicing, Cell adhesion, Complete proteome, Direct protein sequencing, Disulfide bond, Glycoprotein, Immunoglobulin domain, Membrane, Polymorphism, Reference proteome, Repeat, Secreted, Signal, Transmembrane, Transmembrane helix
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Expression

percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
0000000000100000

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16948836humanurinewhole healthy     
16684767humanbloodplasma severe trauma     Identified peptides: 22
16709260humansemenplasma healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
21616181mousecornea  lumican knock-out   0.855 
12724530humanHela cell extractlipid raftspH-resistant raft; detergent-resistant rafthealthy      
16899541ratkidneyinner medullary collecting duct (IMCD) Perfusion-biotinylation or incubation-biotinylation of IMCD     
16449382ratkidneyinner medullary collecting duct (IMCD) Flow through proteins from avidin affinity step of technique 4     
15951573humanlungbronchoalveolar lavage asthma     
15684408mouseplasma membranebrain cortex and hippocampus healthy     
12234320humanurinewhole healthy     
18578523humanPC3 cancer cellsecretion       
23376485humanurinepodocyte healthy     
20334419humanprostateprostate secretion healthy     
19056867humanurineexosome healthy     Identified peptides: 1

Compile date 12-23-2014© PADB initiative