PADB-logoLSSR - molecule cluster A4008MOSC2, MARC2MOSC domain-containing protein 2, mitochondrial precursor

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensMOSC2_HUMANQ969Z333538023614127

Functions and Classifications

GOC:mitochondrial inner membrane, C:mitochondrial outer membrane, C:mitochondrion, C:peroxisome, F:molybdenum ion binding, F:molybdopterin cofactor binding, F:nitrate reductase activity, F:pyridoxal phosphate binding, P:detoxification of nitrogen compound, P:nitrate metabolic process
UniProtAcetylation, Alternative splicing, Complete proteome, Membrane, Mitochondrion, Mitochondrion outer membrane, Molybdenum, Oxidoreductase, Peroxisome, Polymorphism, Reference proteome, Transit peptide
PADBENZ: enzyme, enzymatic properties

Expression

ratios [in rat]
cytosol/nucleusheart/brainkidney/brainliver/brain
 1.271.131.04
percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
33225160211331769

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
21616181mousecornea  lumican knock-out   2.265 
16635246mousebrainPSD (forebrain) healthy      
21170055humanbrainPSD (neocortex) Glial neoplasm/Lesional epilepsy/Colloid cyst     Unique peptides: 7
16928776ratbrain;heart;kidney;livermitochondria healthy      
16899541ratkidneyinner medullary collecting duct (IMCD) Perfusion-biotinylation or incubation-biotinylation of IMCD     
17768142mousekidneyperoxisomeunknownhealthy     
17768142mousekidneyperoxisomeunknownhealthy     
17768142mousekidneyperoxisomal membraneunknownhealthy     
17768142mousekidneyperoxisomal membraneunknownhealthy     
17768142mousekidneyperoxisomeunknownhealthy     
17768142mousekidneyperoxisomeunknownhealthy     
15593129ratkidneyrenal cortex, brush border membrane vesicles healthy     
16615899mouseliverorganelleMitochondrion (Mito)healthy     
15684408mouseplasma membranebrain cortex and hippocampus healthy     
21127740humanurinewhole acute abdominal pain     Identified peptides: 2
23376485humanurinepodocyte healthy     

Compile date 12-23-2014© PADB initiative