PADB-logoLSSR - molecule cluster A3962MYH14, FP17425Myosin-14

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensMYH14_HUMANQ7Z4061995228002600652, 608568, 614369

Functions and Classifications

GOC:axon, C:cytoplasm, C:growth cone, C:myosin complex, C:stress fiber, F:actin-dependent ATPase activity, F:ATP binding, F:microfilament motor activity, P:actin filament-based movement, P:ATP catabolic process, P:axon guidance, P:regulation of cell shape, F:motor activity, P:metabolic process
UniProt3D-structure, Acetylation, Actin-binding, Alternative splicing, ATP-binding, Calmodulin-binding, Cell shape, Coiled coil, Complete proteome, Deafness, Direct protein sequencing, Disease mutation, Motor protein, Myosin, Neuropathy, Non-syndromic deafness, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Expression

percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
1201030754426227

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16684767humanbloodplasma severe trauma     Identified peptides: 3
16901338humantearwhole healthy     
18361515humansalivaParotid healthy     Identified peptides: 3
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
16507876ratbrainPSD (forebrain and cerebellum) healthy     Identified peptides: 2
15020595ratbrainPSD (forebrain) healthy     
21616181mousecornea  lumican knock-out   0.985 
14720225ratbrainPSD forebrain healthy      
16635246mousebrainPSD (forebrain) healthy      
21170055humanbrainPSD (neocortex) Glial neoplasm/Lesional epilepsy/Colloid cyst     Unique peptides: 57
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
16641100ratkidneyinner medullary collecting duct (IMCD) Phosphoproteome of IMCD     
16899541ratkidneyinner medullary collecting duct (IMCD) Perfusion-biotinylation or incubation-biotinylation of IMCD     
17711322humankidneyglomerulus healthy     
17711322humankidneyglomerulus healthy     
15951573humanlungbronchoalveolar lavage asthma     
15684408mouseplasma membranebrain cortex and hippocampus healthy     
21127740humanurinewhole acute abdominal pain     Identified peptides: 27
UNPUBLISHED_1humanurinewhole cancer     
23376485humanurinepodocyte healthy     
UNPUBLISHED_2sheepbrainfrontal cortex healthy     
UNPUBLISHED_2sheepbrainfrontal cortex healthy     
UNPUBLISHED_2sheepbrainfrontal cortex healthy     
UNPUBLISHED_2sheepbrainhippocampus healthy     
UNPUBLISHED_2sheepbrainhippocampus healthy     
UNPUBLISHED_2sheepbrainhippocampus healthy     
UNPUBLISHED_2humanliverwhole, fetal healthy     
UNPUBLISHED_2humanliverwhole, fetal healthy     
UNPUBLISHED_3humanPC3 cancer cellwhole        
18553995humanprostatewhole prostate cancer     Identified peptides: 33
19056867humanurineexosome healthy     Identified peptides: 1
19056867humanurineexosome healthy     Identified peptides: 8

Compile date 12-23-2014© PADB initiative