PADB-logoLSSR - molecule cluster A3823RPS840S ribosomal protein S8

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensRS8_HUMANP6224120724074600357

Functions and Classifications

GOC:cytosolic small ribosomal subunit, F:structural constituent of ribosome, P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, P:SRP-dependent cotranslational protein targeting to membrane, P:translational elongation, P:translational initiation, P:translational termination, P:viral transcription, C:cytoplasm, C:ribosome, P:translation, C:cytosolic small ribosomal subunit
UniProt3D-structure, Complete proteome, Cytoplasm, Direct protein sequencing, Polymorphism, Reference proteome, Ribonucleoprotein, Ribosomal protein, Phosphoprotein
PADBRIB: ribosome

Expression

ratios [in mouse, rat]
cytosol/nucleusheart/brainkidney/brainliver/brain
7.71.04, 1.040.8, 0.80.83, 0.83
percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
0, 0, 0, 0, 0, 0, 0, 04, 6, 6, 5, 5, 5, 5, 54, 6, 6, 5, 5, 5, 5, 54, 6, 6, 5, 5, 5, 5, 50, 0, 0, 0, 0, 0, 0, 046, 24, 24, 33, 33, 45, 45, 500, 0, 0, 0, 0, 0, 0, 00, 0, 0, 0, 0, 0, 0, 04, 24, 24, 5, 5, 5, 5, 50, 0, 0, 0, 0, 0, 0, 08, 0, 0, 10, 10, 0, 0, 00, 0, 0, 0, 0, 0, 0, 08, 12, 12, 14, 14, 10, 10, 923, 24, 24, 24, 24, 25, 25, 23

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
18501002mousekidneycortexCytoplasmhealthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
15020595ratbrainPSD (forebrain) healthy     
21616181mousecornea  lumican knock-out   1.015 
21616181mousecornea  lumican knock-out   1.11 
14720225ratbrainPSD forebrain healthy      
16635246mousebrainPSD (forebrain) healthy      
21170055humanbrainPSD (neocortex) Glial neoplasm/Lesional epilepsy/Colloid cyst     Unique peptides: 3
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
16047384ratbrainPSD pre- and postsynapse (cortex)postsynaptichealthy     Sequence coverage: 7.2
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
16928776ratbrain;heart;kidney;livermitochondria healthy      
16928776ratbrain;heart;kidney;livermitochondria healthy      
12176931humanHela cell extractspliceosome healthy      
12724530humanHela cell extractlipid raftsdetergent-resistant raft; Raft protein; Membrane proteinhealthy      
16381850humanHela cell extractnucleus healthy     theoretical Mr: 25460
15905145ratkidneyinner medullary collecting duct (IMCD) Isolation of AQP-2 containing intracellular vesicles     
16449382ratkidneyinner medullary collecting duct (IMCD) Flow through proteins from avidin affinity step of technique 4     
16691549ratliverGolgi healthy      
16615899mouseliverorganelleEndoplasmic reticulum (ER)|ER/Golgi vesicles (ERGDV)|Recycling endosomes (RE/TGN)|Plasma membrane (Phealthy     
21127740humanurinewhole acute abdominal pain     Identified peptides: 13
23308193humanbladder cancer cell linecytosolic and nuclear fractionation bladder cancer   0.44 
23376485humanurinepodocyte healthy     
UNPUBLISHED_2humanliverwhole, fetal healthy     
UNPUBLISHED_3humanPC3 cancer cellwhole        

Compile date 12-23-2014© PADB initiative