PADB-logoLSSR - molecule cluster A3211CKAP4, P63P63 protein

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensCKAP4_HUMANQ0706560266022 

Functions and Classifications

GOC:cytoskeleton, C:endoplasmic reticulum membrane, C:integral component of membrane, C:lipid particle, C:perinuclear region of cytoplasm, C:plasma membrane, C:integral to membrane
UniProtCell membrane, Coiled coil, Complete proteome, Cytoplasm, Cytoskeleton, Direct protein sequencing, Endoplasmic reticulum, Lipoprotein, Membrane, Palmitate, Phosphoprotein, Polymorphism, Reference proteome, Signal-anchor, Transmembrane, Transmembrane helix
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Expression

percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
00000000290003636

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16446289humanhairshaft healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
21616181mousecornea  lumican knock-out   0.905 
16635246mousebrainPSD (forebrain) healthy      
21170055humanbrainPSD (neocortex) Glial neoplasm/Lesional epilepsy/Colloid cyst     Unique peptides: 17
12724530humanHela cell extractlipid raftspH-resistant raft; detergent-resistant raft; Raft proteinhealthy      
17200159humanhuman mesangial cells (HMC)membrane high glucose growth (HG), simulating diabetes  downregulated0.5875 
16449382ratkidneyinner medullary collecting duct (IMCD) Flow through proteins from avidin affinity step of technique 4     
16899541ratkidneyinner medullary collecting duct (IMCD) Perfusion-biotinylation or incubation-biotinylation of IMCD     
17711322humankidneyglomerulus healthy     
17711322humankidneyglomerulus healthy     
17711322humankidneyglomerulus healthy     
15684408mouseplasma membranebrain cortex and hippocampus healthy     
23308193humanbladder cancer cell linecytosolic and nuclear fractionation bladder cancer   0.28 
UNPUBLISHED_2humanliverwhole, fetal healthy     
UNPUBLISHED_2humanliverwhole, fetal healthy     
UNPUBLISHED_2humanliverwhole, fetal healthy     
UNPUBLISHED_3humanPC3 cancer cellwhole        
18553995humanprostatewhole prostate cancer     Identified peptides: 11
19056867humanurineexosome healthy     Identified peptides: 1

Compile date 12-23-2014© PADB initiative