PADB-logoLSSR - molecule cluster A179ANAE1, APPBP1, HPP1NEDD8 activating enzyme E1 regulatory subunit 1

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensULA1_HUMANQ1356453460246603385

Functions and Classifications

GOC:cytoplasm, C:plasma membrane, F:catalytic activity, P:mitotic DNA replication checkpoint, P:neuron apoptotic process, P:protein neddylation, P:regulation of neuron apoptotic process, P:signal transduction, P:metabolic process, F:nucleotide binding, P:apoptotic process, P:DNA replication, P:mitotic cell cycle DNA replication checkpoint, P:regulation of apoptotic process
UniProt3D-structure, Acetylation, Alternative splicing, Apoptosis, Cell cycle, Cell membrane, Complete proteome, Membrane, Polymorphism, Reference proteome, Ubl conjugation, Ubl conjugation pathway
PADBSIG: signalling

Expression

ratios [in mouse]
cytosol/nucleusheart/brainkidney/brainliver/brain
28   

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
21616181mousecornea  lumican knock-out   1.23 
16861337humanblooderythrocytecytoplasmichealthy     
16615899mouseliverorganelle healthy     

Compile date 12-23-2014© PADB initiative