PADB-logoLSSR - molecule cluster A1586PRSS1, TRP1, TRY1Protease serine 1

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensTRY1_HUMANP0747724726558167800, 276000

Functions and Classifications

GOC:extracellular region, C:extracellular space, F:metal ion binding, F:serine-type endopeptidase activity, P:cobalamin metabolic process, P:digestion, P:extracellular matrix disassembly, P:proteolysis, F:hydrolase activity, P:metabolic process
UniProt3D-structure, Calcium, Complete proteome, Digestion, Direct protein sequencing, Disease mutation, Disulfide bond, Hydrolase, Metal-binding, Polymorphism, Protease, Reference proteome, Secreted, Serine protease, Signal, Sulfation, Zymogen
PADBENZ: enzyme, enzymatic properties

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16948836humanurinewhole healthy     
16948836humanurinewhole healthy     
16709260humansemenplasma healthy     
18361515humansalivaParotid;SMSL healthy     
21616181mousecornea  lumican knock-out   1 
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
15905145ratkidneyinner medullary collecting duct (IMCD) Isolation of AQP-2 containing intracellular vesicles     
16449382ratkidneyinner medullary collecting duct (IMCD) Flow through proteins from avidin affinity step of technique 4     
16691549ratliverGolgi healthy      
15951573humanlungbronchoalveolar lavage asthma     
15951573humanlungbronchoalveolar lavage asthma     
16549904mouseurinewhole membranoproliferative glomerulonephritis model using complement regulatory protein factor H mutant  same0.91 
11680902humanurinewhole healthy     
21127740humanurinewhole acute abdominal pain     Identified peptides: 18
18578523humanPC3 cancer cellsecretion       
23376485humanurinepodocyte healthy     
18553995humanprostatewhole prostate cancer     Identified peptides: 4

Compile date 12-23-2014© PADB initiative