PADB-logoLSSR - molecule cluster A149CMajor urinary protein

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Rattus norvegicusMUP_RATP0276118120737 

Functions and Classifications

GOcytosol, extracellular space, nucleus, insulin-activated receptor activity, pheromone binding, transporter activity, aerobic respiration, cellular response to lipid, energy reserve metabolic process, glucose homeostasis, heat generation, locomotor rhythm, mitochondrion morphogenesis, negative regulation of gluconeogenesis, negative regulation of insulin secretion involved in cellular response to glucose stimulus, negative regulation of lipid biosynthetic process, negative regulation of lipid storage, negative regulation of transcription, DNA-dependent, positive regulation of gene expression, positive regulation of glucose metabolic process, positive regulation of lipid metabolic process, positive regulation of protein kinase B signaling cascade
UniProt3D-structure, Allergen, Complete proteome, Cytoplasm, Direct protein sequencing, Disulfide bond, Glycoprotein, Pheromone-binding, Secreted, Signal, Transport
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
12234301ratkidneyCortex;Medulla healthy      
18167449ratkidneywhole diabetes   0.62 
15047867ratliverGolgi healthy     Sequence coverage: 31.5
15047867ratliverGolgi healthy     Sequence coverage: 31.5
15047867ratliverGolgi healthy     Sequence coverage: 63.5
17000643ratliverinner mitochondrial membrane healthy     
16691549ratliverGolgi healthy      
16691549ratliverGolgi healthy      
16691549ratliverGolgi healthy      
12582004raturinewhole 2.7% NaCl feeding of rats   4.78  
14610326raturinewhole healthy     
14610326raturinewhole healthy     
14610326raturinewhole healthy     
17081055raturinewhole Membranous Nephropathy (primary glomerular disease) induced in rat model  downregulated0.047020341 
17616219raturinewhole Passive Heymann Nephritis  downregulated0.059701493 
12582004raturinewhole 2.7% NaCl feeding of rats   2.51  
14610326raturinewhole healthy     
18324733raturinewhole healthy     
18324733raturinewhole healthy     
18324733raturinewhole healthy     
18324733raturinewhole healthy     
17021608raturineexosome acute kidney injury  up  
18440303raturineglycoproteins glomerular disease/adriamycin nephropathy and Thy1.1 glomerulonephritis   0.77
18440303raturineglycoproteins glomerular disease/adriamycin nephropathy and Thy1.1 glomerulonephritis   0.00
18440303raturineglycoproteins glomerular disease/adriamycin nephropathy and Thy1.1 glomerulonephritis   >100
18440303raturineglycoproteins glomerular disease/adriamycin nephropathy and Thy1.1 glomerulonephritis   >100
18440303raturineglycoproteins glomerular disease/adriamycin nephropathy and Thy1.1 glomerulonephritis   0.00
18440303raturineglycoproteinscytoplasmaglomerular disease/adriamycin nephropathy and Thy1.1 glomerulonephritis   >100
18440303raturineglycoproteins glomerular disease/adriamycin nephropathy and Thy1.1 glomerulonephritis   >100
18440303raturineglycoproteins glomerular disease/adriamycin nephropathy and Thy1.1 glomerulonephritis   >100
18440303raturineglycoproteins glomerular disease/adriamycin nephropathy and Thy1.1 glomerulonephritis   >100
18440303raturineglycoproteins glomerular disease/adriamycin nephropathy and Thy1.1 glomerulonephritis   >100
18440303raturineglycoproteins glomerular disease/adriamycin nephropathy and Thy1.1 glomerulonephritis   >100

Compile date 12-23-2014© PADB initiative