PADB-logoLSSR - molecule cluster A1331EHD3, EHD2, PAST3EH-domain containing protein 3

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensEHD3_HUMANQ9NZN354661896605891

Functions and Classifications

GOC:endocytic vesicle, C:nucleus, C:perinuclear region of cytoplasm, C:plasma membrane, C:recycling endosome membrane, F:ATP binding, F:calcium ion binding, F:GTP binding, F:GTPase activity, F:nucleic acid binding, P:blood coagulation, P:endocytic recycling, P:GTP catabolic process, P:protein homooligomerization, P:protein targeting to plasma membrane, P:regulation of cardiac muscle cell membrane potential
UniProtAcetylation, ATP-binding, Calcium, Cell membrane, Coiled coil, Complete proteome, Cytoplasm, Direct protein sequencing, Endosome, Membrane, Metal-binding, Nucleotide-binding, Reference proteome, Phosphoprotein
PADBUK: unknown

Expression

percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
000330330170000017

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
18501002mousekidneycortexCytoplasmhealthy     
16684767humanbloodplasma severe trauma     Identified peptides: 4
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
21616181mousecornea  lumican knock-out   0.795 
16635246mousebrainPSD (forebrain) healthy      
21170055humanbrainPSD (neocortex) Glial neoplasm/Lesional epilepsy/Colloid cyst     Unique peptides: 12
16047384ratbrainPSD pre- and postsynapse (cortex)presynaptichealthy     Sequence coverage: 3.2
15668994humankidneyglomerulus healthy     
15668994humankidneyglomerulus healthy     
17711322humankidneyglomerulus healthy     
17711322humankidneyglomerulus healthy     
17000643ratliverinner mitochondrial membrane healthy     
16615899mouseliverorganelleER/Golgi vesicles (ERGDV)|Recycling endosomes (RE/TGN)healthy     
15951573humanlungbronchoalveolar lavage asthma     
15684408mouseplasma membranebrain cortex and hippocampus healthy     
15326289humanurineexosomecytoplasm (endosomal trafficking) healthy     
21127740humanurinewhole acute abdominal pain     Identified peptides: 48
UNPUBLISHED_2sheepbrainfrontal cortex healthy     
UNPUBLISHED_2sheepbrainfrontal cortex healthy     

Compile date 12-23-2014© PADB initiative