PADB-logoLSSR - molecule cluster A0854PAWR, PAR4Prostate apoptosis response protein PAR-4

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensPAWR_HUMANQ96IZ034036568601936

Functions and Classifications

GOC:cytoplasm, C:nucleus, C:plasma membrane, F:actin binding, F:enzyme binding, F:transcription corepressor activity, P:actin filament bundle assembly, P:apoptotic process, P:apoptotic signaling pathway, P:interleukin-2 biosynthetic process, P:negative regulation of B cell proliferation, P:negative regulation of cell proliferation, P:negative regulation of T cell proliferation, P:negative regulation of T cell receptor signaling pathway, P:negative regulation of transcription from RNA polymerase II promoter, P:positive regulation of amyloid precursor protein biosynthetic process, P:positive regulation of apoptotic process, P:transcription, DNA-templated, C:cytoplasm, "C:actin filament, P:induction of apoptosis, P:transcription, DNA-dependent", C:actin filament
UniProt3D-structure, Apoptosis, Coiled coil, Complete proteome, Cytoplasm, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Transcription, Transcription regulation
PADBSIG: signalling

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
18501002mousekidneycortexNucleushealthy     
16684767humanbloodplasma severe trauma     Identified peptides: 1
21616181mousecornea  lumican knock-out   1.01 
17711322humankidneyglomerulus healthy     
23308193humanbladder cancer cell linecytosolic and nuclear fractionation bladder cancer   0.71 
18553995humanprostatewhole prostate cancer     Identified peptides: 10

Compile date 12-23-2014© PADB initiative