PADB-logoLSSR - molecule cluster A0703ARHGDIB, GDIA2, GDID4Rho GDP-dissociation inhibitor 2

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensGDIR2_HUMANP5256620122988602843

Functions and Classifications

GOC:cytoplasmic membrane-bounded vesicle, C:cytoskeleton, C:cytosol, F:GTPase activator activity, F:Rho GDP-dissociation inhibitor activity, P:actin cytoskeleton organization, P:cellular component movement, P:immune response, P:multicellular organismal development, P:negative regulation of cell adhesion, P:positive regulation of GTPase activity, P:regulation of small GTPase mediated signal transduction, P:Rho protein signal transduction, C:cytoplasm, P:regulation of catalytic activity
UniProt3D-structure, Acetylation, Complete proteome, Cytoplasm, Direct protein sequencing, GTPase activation, Phosphoprotein, Reference proteome
PADBUK: unknown

Expression

percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
330170000017000033

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16948836humanurinewhole healthy     
18501002mousekidneycortexCytoplasmhealthy     
16684767humanbloodplasma severe trauma     Identified peptides: 6
16901338humantearwhole healthy     
18361515humansalivaParotid;SMSL healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
15253431humanheartmitochondria healthy     Unique peptides: 2
21616181mousecornea  lumican knock-out   1.02 
15668994humankidneyglomerulus healthy     
15668994humankidneyglomerulus healthy     
15668994humankidneyglomerulus healthy     
15668994humankidneyglomerulus healthy     
16449382ratkidneyinner medullary collecting duct (IMCD) Flow through proteins from avidin affinity step of technique 4     
17711322humankidneyglomerulus healthy     
15951573humanlungbronchoalveolar lavage asthma     
16816363humanlungbronchoalveolar lavageCellular, cytosolic vesicleacute respiratory distress syndrome     Unique peptides: 166
17518487humanurinewholecytoplasm bladder cancer     
23376485humanurinepodocyte healthy     
23376485humanurinepodocyte healthy     
18553995humanprostatewhole prostate cancer     Identified peptides: 5
20334419humanprostateprostate secretion healthy     
19056867humanurineexosome healthy     Identified peptides: 1

Compile date 12-23-2014© PADB initiative