cvd-logocvd - Study ID Exp24530965

PubMed ID24530965
AuthorsHolven KB, Narverud I, Lindvig HW, Halvorsen B, Langslet G, Nenseter MS, Ulven SM, Ose L, Aukrust P, Retterstol K.
TitleSubjects with familial hypercholesterolemia are characterized by an inflammatory phenotype despite long-term intensive cholesterol lowering treatment.
JournalAtherosclerosis. 2014 Apr;233(2):561-7
AbstractOBJECTIVE: The atherosclerotic process is driven by elevated Low-density lipoprotein (LDL)-cholesterol in combination with enhanced inflammatory responses. Several mediators participate in this complex inflammatory network including members of the tumour necrosis factor (receptor) superfamily. Familial hypercholesterolemia (FH) is associated with increased risk of developing premature atherosclerosis. Statin treatment may normalize LDL-cholesterol levels, but it is not known if the inflammatory responses are normalized in statin-treated FH patients. METHODS: In long-term statin-treated FH subjects (n=33) and healthy controls (n=10) the expression of tumour necrosis factor (receptor) superfamily related genes in peripheral blood mononuclear cells (PBMC) were analyzed by real-time quantitative RT-PCR. TNFa release was measured in PBMC from patients and controls by immunoassay. RESULTS: In FH patients with normal LDL-cholesterol, after a median of 17 years of statin treatment, our major findings were: (i) Gene expression of CD137, LIGHT (lymphotoxins inducible expression, competes with HSV glycoprotein D for HVEM, a receptor expressed on T-lymphocytes), HVEM (Herpesvirus entry mediator), the two TNFa Receptors (TNFR1 and TNFR2), TNF related apoptosis inducing ligand (TRAIL) and CD40 were increased in PBMC from FH patients compared to controls. (ii) The release of TNFa in PBMC from FH patients, in response to LPS was increased compared to controls. (iii) PBMC from FH patients had enhanced spontaneous release of TNFa when incubated in the presence of control serum and in particular in the presence of FH serum. CONCLUSION: Despite long-term statin therapy, an increased expression of several TNF related genes in PBMC isolated from FH patients was observed. Our findings may implicate a pathogenic role for inflammation and TNF related molecules in FH, and these findings suggest the possibility that novel treatment modalities beyond that of statins and lipid lowering drugs may be useful in FH subjects.

Sample characteristics

SpeciesTissue / SourceCompartmentDiseaseNDetection methodSample
Homo sapiensbloodmononuclear cells (PBMCs)CAD23Gene-arrayDem24530965

Sample description and preparation

N (case)13
N (control)10
Disease (case)Familial Hypercholesterolemia and Coronary artery disease (CAD)

Sample detection

Array versionAffymetrix Human Genome U133 Plus 2.0 Array

Sample analysis

Software thresholdP<0.05

Molecule list

Molecule IDextExternal IDGeneNameSource accRegulation (case/control)Scores
A0008 CALM_HUMANCALM1, CALM2, CALM3CalmodulinGDS3669
A0012 PLCG1_HUMANPLCG1, PLC11-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1GDS3669
A0015 DLG1_HUMANDLG1, SAP97Disks large homolog 1GDS3669
A0021 PTN4_HUMANPTPN4Protein tyrosine phosphatase, non-receptor type 4GDS3669
A002C GLRX1_HUMANGLRX, GRXGlutaredoxin-1GDS3669
A0034 RPGF2_HUMANRAPGEF2, NRAPGEP, PDZGEF1RAP guanine nucleotide exchange factor 2GDS3669
A0043 GNAO_HUMANGNAO1Guanine nucleotide-binding protein G(O), alpha subunit 1GDS3669
A0052 GNAZ_HUMANGNAZGuanine nucleotide-binding protein G(z), alpha subunitGDS3669
A0053 GBG2_HUMANGNG2Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunitGDS3669
A005H KCD21_HUMANKCTD21BTB/POZ domain-containing protein KCTD21GDS3669
A0066 GBG11_HUMANGNG11, GNGT11Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-11 subunitGDS3669
A006G CSRN1_HUMANCSRNP1, AXUD1, TAIP3Cysteine/serine-rich nuclear protein 1GDS3669
A0070 GBB2_HUMANGNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 2GDS3669
A0097 TLN1_HUMANTLN1, TLNTalin 1GDS3669
A0098XVINC_HUMANVCLVinculinGDS3669
A0105 HOME2_HUMANHOMER2Homer protein homolog 2GDS3669
A010C GOT1B_HUMANGOLT1B, GOT1A, CGI-141Vesicle transport protein GOT1BGDS3669
A0114 AT2B4_HUMANATP2B4, MXRA1Plasma membrane calcium-transporting ATPase 4GDS3669
A012A NEUG_HUMANNRGNNeurograninGDS3669
A0133 DYHC1_HUMANDYNC1H1, Dnchc1, DHC1Dynein heavy chain, cytosolicGDS3669
A0156 EGFR_HUMANEGFR, ERBB, ERBB1Epidermal growth factor receptor precursorGDS3669
A015B SMAD6_HUMANSMAD6, MADH6Mothers against decapentaplegic homolog 6GDS3669
A0169 PDE4D_HUMANHSPDE4D, PDE4DN2, PDE4DcAMP-specific 3',5'-cyclic phosphodiesterase 4DGDS3669
A0174 M3K1_HUMANMAP3K1, MAPKKK1, MEKKMitogen-activated protein kinase kinase kinase 1GDS3669
A0175 GAB2_HUMANGAB2Grb2-associated binding protein 2GDS3669
A0176 PAK1_HUMANPAK1, PAK1BSerine/threonine-protein kinase PAK 1GDS3669
A0179 WIPF1_HUMANWIPF1, WASPIP, WIPWAS/WASL-interacting protein family member 1GDS3669
A0180 GAB1_HUMANGAB1GRB2-associated-binding protein 1GDS3669
A018C HBG1_HUMANHBG1, PRO2979Hemoglobin subunit gamma 1Hemoglobin gamma-A and gamma-G chainsGDS3669
A0195 INSR_HUMANINSRInsulin receptorGDS3669
A0224 FSCN1_HUMANFSCN1, FAN1, HSNFascin 1GDS3669
A0235 ARP2_HUMANACTR2, ARP2Actin-like protein 2GDS3669
A0236 WASL_HUMANWASLNeural Wiskott-Aldrich syndrome proteinGDS3669
A023I R144B_HUMANRNF144B, IBRDC2, P53RFPE3 ubiquitin-protein ligase RNF144BGDS3669
A0247 WASP_HUMANWAS, IMD2, WASPWiskott-Aldrich syndrome proteinGDS3669
A024J TTC9C_HUMANTTC9CTetratricopeptide repeat protein 9CGDS3669
A0252 AP2A2_HUMANAP2A2, ADTAB, CLAPA2Adapter-related protein complex 2 alpha 2 subunitGDS3669
A0270 GRB10_HUMANGRB10, GRBIRGrowth factor receptor-bound protein 10GDS3669
A0312 CREM_HUMANCREM, hCREM-1, ICERcAMP responsive element modulatorGDS3669
A0314 CREB1_HUMANCREB1, CREB-1, CREB-1cAMP response element binding proteinGDS3669
A031J TTP_HUMANZFP36, G0S24, RNF162ATristetraprolineGDS3669
A0324 PLAK_HUMANJUP, CTNNG, DP3Junction plakoglobinGDS3669
A0367 RL13_HUMANRPL13, BBC160S ribosomal protein L13GDS3669
A0375 NFL_HUMANNEFL, NF68, NFLNeurofilament triplet L proteinGDS3669
A0386 AT5G1_HUMANATP5G1ATP synthase lipid-binding protein, mitochondrial precursorGDS3669
A0420 ABLM1_HUMANABLIM1, ABLIM, LIMAB1Actin-binding LIM protein 1GDS3669
A0428 ALDOC_HUMANALDOC, ALDCFructose-bisphosphate aldolase CGDS3669
A042A PERQ2_HUMANGIGYF2, TNRC15, PERQ2PERQ amino acid-rich with GYF domain-containing protein 2GDS3669
A042F C42S2_HUMANCDC42SE2, SPEC2CDC42 small effector protein 2GDS3669
A0432 PRDX6_HUMANPRDX6, AOP2Peroxiredoxin 6GDS3669
A043C IMB1_HUMANKPNB1, NTF97Importin beta-1 subunitGDS3669
A0441 FABP5_HUMANFABP5Fatty acid binding protein 5 (psoriasis-associated)GDS3669
A0469 CTND2_HUMANCTNND2, NPRAPCatenin delta-2GDS3669
A0472 PPR1B_HUMANPPP1R1B, DARPP32Protein phosphatase 1 regulatory subunit 1BGDS3669
A0479 MCL1_HUMANMCL1, BCL2L3Induced myeloid leukemia cell differentiation protein Mcl-1GDS3669
A047J TXNIP_HUMANTXNIP, VDUP1, GENEThioredoxin interacting proteinGDS3669
A0480 B2LA1_HUMANBCL2A1, BCL2L5, BFL1Bcl-2-related protein A1GDS3669
A0485 PGH2_HUMANPTGS2, COX-2, COX2Prostaglandin G/H synthase 2 precursorGDS3669
A0489 MK10_HUMANMAPK10, JNK3, JNK3AMitogen-activated protein kinase 10GDS3669
A0500 NCF1_HUMANNCF1, NOXO2, SH3PXD1ANeutrophil cytosol factor 1GDS3669
A050D UQCC2_HUMANUQCC2, MNF1Uncharacterized proteinGDS3669
A0514 DYL1_HUMANDNCL1, DYNLL1, DLC1Dynein light chain 1, cytoplasmicGDS3669
A0517 CXCR4_HUMANCXCR4C-X-C chemokine receptor type 4GDS3669
A051J TYSY_HUMANTYMS, TSThymidylate synthaseGDS3669
A0530 SOCS3_HUMANSOCS3, CIS3, SSI3Suppressor of cytokine signaling 3GDS3669
A054G CXXC5_HUMANCXXC5, HSPC195, TCCCIA00297CXXC-type zinc finger protein 5GDS3669
A056G CYTIP_HUMANCYTIP, PSCDBPCytohesin-interacting proteinGDS3669
A0577 STON2_HUMANSTON2, STN2, STNBStonin 2GDS3669
A0579 DCC_HUMANDCC, IGDCC1Netrin receptor DCCGDS3669
A0586 AA2BR_HUMANADORA2BAdenosine A2b receptorGDS3669
A0589 RABE1_HUMANRABEP1, RAB5EP, RABPT5Rab GTPase-binding effector protein 1GDS3669
A058G D19L3_HUMANDPY19L3Protein DPY-19 homolog 3GDS3669
A0608 EREG_HUMANEREGProepiregulin precursorGDS3669
A0609 EGF_HUMANEGFPro-epidermal growth factor precursorGDS3669
A060F KIME_HUMANMVKMevalonate kinaseGDS3669
A060H KLH35_HUMANKLHL35KELCH-like protein 35GDS3669
A060J U2AFM_HUMANZRSR2, U2AF1-RS2, U2AF1L2U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit related-protein 2GDS3669
A0613 5HT2B_HUMANHTR2B5-hydroxytryptamine 2B receptorGDS3669
A0614 TSC2_HUMANTSC2, TSC4TuberinGDS3669
A0619 RB11A_HUMANRAB11A, RAB11, 24KGRas-related protein Rab-11AGDS3669
A062D MASU1_HUMANMALSU1IOJAP-related protein family proteinGDS3669
A062G DACT1_HUMANDACT1, DPR1, HNG3Dapper 1GDS3669
A0686 AP1B1_HUMANAP1B1, ADTB1, BAM22AP-1 complex subunit beta-1GDS3669
A0688 AP1M1_HUMANAP1M1, CLTNMAdaptor-related protein complex 1, mu 1 subunitGDS3669
A0691 AP1S1_HUMANAP1S1, AP19, CLAPS1Adapter-related protein complex 1 sigma 1A subunitGDS3669
A0698 ZYX_HUMANZYX, ESP-2ZyxinGDS3669
A069B T22D3_HUMANTSC22D3, DSIPI, GILZGlucocorticoid-induced leucine zipper proteinGDS3669
A070D CPED1_HUMANCPED1, UNQ9432/PRO34713, VCRP9432Uncharacterized protein C7ORF58GDS3669
A0713 P55G_HUMANPIK3R3Phosphatidylinositol 3-kinase regulatory gamma subunitGDS3669
A0719 STAT1_HUMANSTAT1Signal transducer and activator of transcription 1-alpha/betaGDS3669
A072H KPCD2_HUMANPKD2, PRKD2, HSPC187Serine/threonine-protein kinase D2GDS3669
A072J UBE2C_HUMANUBE2C, UBCH10Ubiquitin-conjugating enzyme E2 CGDS3669
A073I RCAN2_HUMANRCAN2, DSCR1L1, ZAKI4Calcipressin-2GDS3669
A0752 UTRO_HUMANUTRN, UTRNB, DMDLUtrophinGDS3669
A076C KISHA_HUMANTMEM167A, TMEM167Protein kish-AGDS3669
A076D TDRP_HUMANTDRP2, INM01Uncharacterized protein C8orf42GDS3669
A077C KISHB_HUMANTMEM167B, AD-020Transmembrane protein 167BGDS3669
A0782 NUMA1_HUMANNuMA, NUMA1, NUMANuMA proteinGDS3669
A0786 OPSD_HUMANrhodopsin, RHO, OPN2RhodopsinGDS3669
A079AXRAP1B_HUMANRAP1B, PNAS-140Ras-related protein Rap-1bGDS3669
A0812 ADRB2_HUMANADRB2, ADRB2R, B2ARBeta-2 adrenergic receptorGDS3669
A082K OR1F1_HUMANOR16-90, OR16-89, OR16-36Olfactory receptor 1F1GDS3669
A0836 HGS_HUMANHGS, HRS, IMOS-1Hepatocyte growth factor-regulated tyrosine kinase substrateGDS3669
A0869 IKKB_HUMANIKBKB, IKKBInhibitor of nuclear factor kappa B kinase beta subunitGDS3669
A0875 IL1R1_HUMANIL1R1, IL1R, IL1RAInterleukin-1 receptor, type I precursorGDS3669
A0881 CFLAR_HUMANCFLAR, CASH, CASP8AP1CASP8 and FADD-like apoptosis regulator precursorGDS3669
A0885 CKS2_HUMANCKS2Cyclin-dependent kinases regulatory subunit 2GDS3669
A0912 TNAP3_HUMANTNFAIP3, OTUD7CTumor necrosis factor, alpha-induced protein 3GDS3669
A091F TP4A1_HUMANPTP4A1, PRL1, PTPCAAX1Protein tyrosine phosphatase PTPCAAX1GDS3669
A0922 NCOR2_HUMANNCOR2, CTG26Nuclear receptor co-repressor 2GDS3669
A0928 CCNB1_HUMANCCNB1, CCNBG2/mitotic-specific cyclin B1GDS3669
A0929 CCNB2_HUMANCCNB2G2/mitotic-specific cyclin B2GDS3669
A092F TBCD4_HUMANTBC1D4, AS160TBC1 domain family member 4GDS3669
A093B TCP4_HUMANSUB1, PC4, RPO2TC1Activated RNA polymerase II transcriptional coactivator p15GDS3669
A094H KTBL1_HUMANKATNBL1Uncharacterized protein C15ORF29GDS3669
A0957 CISH_HUMANCISH, G18, SOCSCytokine-inducible SH2-containing proteinGDS3669
A095G DDIT4_HUMANDDIT4, REDD1, RTP801DNA-damage-inducible transcript 4 proteinGDS3669
A0961 ELOC_HUMANTCEB1Transcription elongation factor B polypeptide 1GDS3669
A0965 WSB1_HUMANWSB1, SWIP1WD repeat and SOCS box containing protein 1GDS3669
A0968 RBX1_HUMANRBX1, RNF75, ROC1RING-box protein 1GDS3669
A0972 RB_HUMANRB1Retinoblastoma-associated proteinGDS3669
A0983 PP1RB_HUMANPPP1R11, HCGV, TCTE5Protein phosphatase 1, regulatory (inhibitor) subunit 11GDS3669
A099C LYST_HUMANLYST, CHS, CHS1Lysosomal trafficking regulatorGDS3669
A1025 LATS1_HUMANLATS1, WARTSLarge tumor suppressor 1GDS3669
A103B TF2AA_HUMANGTF2A1, TF2A1Transcription initiation factor IIA subunit 1GDS3669
A1042 MYCB2_HUMANMYCBP2, PAM, HSPC026MYC binding protein 2GDS3669
A1044 RBP2_HUMANRANBP2, NUP358Ran-binding protein 2GDS3669
A1050 HIPK2_HUMANHIPK2, PRO0593Homeodomain-interacting protein kinase 2GDS3669
A1055 MAD1_HUMANMXD1, MADMAX dimerization protein 1GDS3669
A1056 MAX_HUMANMAX, max, BHLHD4Max proteinGDS3669
A1057 RBBP4_HUMANRBBP4, RBAP48Retinoblastoma-binding protein 4GDS3669
A105F APEX2_HUMANAPEX2, APE2, APEXL2DNA-(apurinic or apyrimidinic site) lyase 2GDS3669
A105G DEN1B_HUMANDENND1B, FAM31BDENN domain-containing protein 1BGDS3669
A1060XH4_HUMANHIST1H4A, HIST1H4B, HIST1H4CHistone H4GDS3669
A1075 WASF2_HUMANWASF2, WAVE2Wiskott-Aldrich syndrome protein family member 2GDS3669
A1076 RGAP1_HUMANRACGAP1, MGCRACGAPGTPase activating protein RACGAP1GDS3669
A107G DEP1B_HUMANDEPDC1B, XTP8DEP domain-containing protein 1BGDS3669
A1081 UPAR_HUMANPLAUR, MO3, UPARUrokinase plasminogen activator surface receptor precursorGDS3669
A1126 CD38_HUMANCD38ADP-ribosyl cyclase 1GDS3669
A1144 SCAM1_HUMANSCAMP1, SCAMPSecretory carrier-associated membrane protein 1GDS3669
A1148 MDM2_HUMANMDM2, HDM2, mdm2Ubiquitin-protein ligase E3 Mdm2GDS3669
A1159 GIPC1_HUMANGIPC1, GIPC, RGS19IP1RGS19-interacting protein 1GDS3669
A1162 RGS10_HUMANRGS10Regulator of G-protein signaling 10GDS3669
A116J USB1_HUMANUSB1UPF0406 protein C16ORF57GDS3669
A1174 LDLR_HUMANldlr, LDLRLow-density lipoprotein receptor precursorGDS3669
A117G DFNA5_HUMANDFNA5, ICERE1Nonsyndromic hearing impairment protein 5GDS3669
A1186 CD4_HUMANCD4T-cell surface glycoprotein CD4 precursorGDS3669
A1188 KLF3_HUMANKLF3, BKLFKruppel-like factor 3GDS3669
A1200 PTPRE_HUMANPTPREProtein-tyrosine phosphatase epsilon precursorGDS3669
A121H LERL1_HUMANLEPROTL1, My047, UNQ577/PRO1139Leptin receptor overlapping transcript-like 1GDS3669
A1232 TNR11_HUMANTNFRSF11A, RANKTumor necrosis factor receptor superfamily member 11A precursorGDS3669
A123BXTNR6A_HUMANTNRC6A, TNRC6, GW1Trinucleotide repeat-containing gene 6A proteinGDS3669
A1254 GGT7_HUMANGGT7, GGTL3, GGTL5Gamma-glutamyltransferase 7GDS3669
A1259 WASF3_HUMANWASF3, SCAR3, WAVE3Wiskott-Aldrich syndrome protein family member 3GDS3669
A1280 IL21R_HUMANIL21R, NILR, UNQ3121/PRO10273Interleukin 21 receptor precursorGDS3669
A1286 JUN_HUMANJUNTranscription factor AP-1GDS3669
A128K KBTB2_HUMANKBTBD2, BKLHD1, CGI-73BTB and Kelch domain containing protein 1GDS3669
A1292 UBE2N_HUMANUBE2N, BLUUbiquitin-conjugating enzyme E2 NGDS3669
A1298 6PGL_HUMANPGLS6-phosphogluconolactonaseGDS3669
A129A SHCBP_HUMANSHCBP1SHC SH2 domain-binding protein 1GDS3669
A1300 DGKZ_HUMANDGKZ, DAGK6Diacylglycerol kinase, zetaGDS3669
A130B TRI14_HUMANTRIM14Tripartite motif protein 14GDS3669
A132G DJB14_HUMANDNAJB14, UNQ9427/PRO34683, EGNR9427DNAJ homolog subfamily B member 14GDS3669
A1336 RIPK2_HUMANRIPK2, CARDIAK, RICKReceptor-interacting serine/threonine protein kinase 2GDS3669
A135J VNN3_HUMANVNN3Vascular non-inflammatory molecule 3 precursorGDS3669
A136I RMD5A_HUMANRMND5AProtein RMD5 homolog AGDS3669
A1373 H31_HUMANHIST1H3A, H3FA, HIST1H3BHistone H3GDS3669
A1375 FOS_HUMANFOS, G0S7Proto-oncogene protein c-fosGDS3669
A1396 MSH6_HUMANMSH6, GTBPDNA mismatch repair protein MSH6GDS3669
A139K MS4A7_HUMANMS4A7, 4SPAN2, CD20L4Membrane-spanning 4-domains subfamily A member 7GDS3669
A1416 TFEC_HUMANTFEC, BHLHE34, TCFECTranscription factor ECGDS3669
A1449 LYL1_HUMANLYL1, BHLHA18Lyl-1 proteinGDS3669
A146G DNJ5B_HUMANDNAJC5BDnaJ homolog subfamily C member 5BGDS3669
A148F TM158_HUMANTMEM158, HBBP, RIS1Transmembrane protein 158GDS3669
A149B UIMC1_HUMANUIMC1, RAP80, RXRIP110BRCA1-A complex subunit RAP80GDS3669
A1504 CD36_HUMANCD36, GP3B, GP4Platelet glycoprotein 4GDS3669
A152G DNSL2_HUMANDNASE1L2, DHP1, DNAS1L2DNase I homolog protein DHP1 precursorGDS3669
A1533 SPRC_HUMANSPARC, ONSPARC precursorGDS3669
A1546 TFPI1_HUMANTFPI, LACI, TFPI1Tissue factor pathway inhibitor precursorGDS3669
A1573 CCR2_HUMANCCR2, CMKBR2C-C chemokine receptor type 2GDS3669
A157C MY18B_HUMANMYO18BMyosin XVIIIBGDS3669
A1580XLYAM1_HUMANL-selectin, SELL, LNHRL-selectin precursorGDS3669
A1592 F13A_HUMANF13A1, F13ACoagulation factor XIII A chain precursorGDS3669
A1609XCALR_HUMANCALR, CRTCCalreticulin precursorGDS3669
A1629 COLI_HUMANPOMC, NPPCorticotropin-lipotropin precursorGDS3669
A1638 CEBPD_HUMANCEBPDCCAAT/enhancer binding protein deltaGDS3669
A166C MYL9_HUMANMYL9, MLC2, MRLC1Myosin regulatory light polypeptide 9GDS3669
A166H LPAR6_HUMANLPAR6, P2RY5Lysophosphatidic acid receptor 6GDS3669
A1674 CO4A6_HUMANCOL4A6Collagen alpha 6(IV) chain precursorGDS3669
A1687 ITAX_HUMANITGAX, CD11CIntegrin alpha-X precursorGDS3669
A1717 ITBP1_HUMANITGB1BP1, ICAP1, ICAP-1AIntegrin beta-1 binding protein 1GDS3669
A1719 TGFR2_HUMANTGFBR2, Tbeta RIIC, TbetaRIICTGF-beta receptor type II precursorGDS3669
A171A TRIA1_HUMANTRIAP1, 15E1.1, HSPC132TP53-regulated inhibitor of apoptosis 1GDS3669
A1729 M3K11_HUMANMAP3K11, MLK3, PTK1Mitogen-activated protein kinase kinase kinase 11GDS3669
A1736 C5AR1_HUMANC5AR1, C5AR, C5R1C5a anaphylatoxin chemotactic receptor 1GDS3669
A174B WIBG_HUMANWIBG, PYMPartner of Y14 and MAGOGDS3669
A1775 TIMP2_HUMANTIMP2Metalloproteinase inhibitor 2 precursorGDS3669
A1777 COAA1_HUMANCOL10A1Collagen alpha 1(X) chain precursorGDS3669
A1778 HBEGF_HUMANHBEGF, DTR, DTSProheparin-binding EGF-like growth factorGDS3669
A1795 CXCL2_HUMANMGSA beta, CXCL2, GRO2C-X-C motif chemokine 2GDS3669
A179F APCD1_HUMANAPCDD1, DRAPC1, FP7019Adenomatosis polyposis coli down-regulated 1GDS3669
A1818 TAP1_HUMANTAP1, TAP1*0102N, ABCB2Antigen peptide transporter 1GDS3669
A1831 KLRD1_HUMANKLRD1, CD94Natural killer cells antigen CD94GDS3669
A183K ZNHI3_HUMANZNHIT3, TRIP3Zinc finger HIT domain-containing protein 3GDS3669
A1841 HBE_HUMANHBE1, HBEHemoglobin epsilon chainGDS3669
A184B Z385A_HUMANZNF385A, HZF, RZFZinc finger protein 385AGDS3669
A185I RNH2C_HUMANRNASEH2C, AYP1Ribonuclease H2 subunit CGDS3669
A188I RNS12_HUMANRNASE12Ribonuclease 12GDS3669
A190J XCT_HUMANxCT, hxCT, SLC7A11Cystine/glutamate transporterGDS3669
A1928 DYN3_HUMANDNM3Dynamin 3GDS3669
A1948 MGST3_HUMANMGST3Microsomal glutathione S-transferase 3GDS3669
A194G DUS28_HUMANDUSP28Similar to Dual specificity protein phosphatase 14GDS3669
A1957 GSTM4_HUMANGSTM4, GSTGlutathione S-transferase mu 4GDS3669
A1964 GSTT1_HUMANGSTT1Glutathione S-transferase theta 1GDS3669
A1969 GSTO1_HUMANGSTO1, GSTTLP28Glutathione transferase omega 1GDS3669
A196H LRFN4_HUMANLRFN4, SALM3Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursorGDS3669
A2007 HSP71_HUMANHSPA1A, HSPA1B, HSPA1Heat shock 70 kDa protein 1GDS3669
A2012 ERG24_HUMANTM7SF2, ANG1Delta(14)-sterol reductaseGDS3669
A2013 DHCR7_HUMANDHCR7, D7SR7-dehydrocholesterol reductaseGDS3669
A2036 CHD2_HUMANCHD2Chromodomain-helicase-DNA-binding protein 2GDS3669
A2043 CHD9_HUMANCHD9, KISH2, PRIC320Chromodomain Helicase DNA binding protein 9GDS3669
A2046 SMCA4_HUMANSMARCA4, BAF190A, BRG1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A4GDS3669
A2047 SMCA2_HUMANSMARCA2, BAF190B, BRMPossible global transcription activator SNF2L2GDS3669
A205B ZC3HD_HUMANZC3H13Zinc finger CCCH domain-containing protein 13GDS3669
A2062 ATRX_HUMANATRX, RAD54L, XH2Transcriptional regulator ATRXGDS3669
A2072 WDR5B_HUMANWDR5BWD repeat-containing protein 5BGDS3669
A209A AFF4_HUMANAFF4, AF5Q31, MCEFAF5q31 proteinGDS3669
A2136 FZR_HUMANFZR1, CDH1, FYRFizzy-related protein homologGDS3669
A2137 CDC20_HUMANCDC20Cell division cycle protein 20 homologGDS3669
A215H LST8_HUMANGBL, MLST8, LST8Target of Rapamycin complex subunit LST8GDS3669
A219G EAF1_HUMANEAF1ELL-associated factor 1GDS3669
A220G EAF2_HUMANEAF2, TRAITS, BM-040ELL-associated factor 2GDS3669
A220J YPEL5_HUMANYPEL5, CGI-127Yippee-like protein 5GDS3669
A2222 BRD4_HUMANBRD4, HUNK1Bromodomain-containing protein 4GDS3669
A222A ARI5B_HUMANARID5B, DESRT, MRF2AT-rich interactive domain-containing protein 5BGDS3669
A223E RB27B_HUMANRAB27BRas-related protein Rab-27BGDS3669
A225H LY96_HUMANLY96, MD2, ESOP1Lymphocyte antigen 96GDS3669
A2270 FGL2_HUMANFGL2Fibroleukin precursorGDS3669
A2278 KCTD6_HUMANKCTD6Potassium channel tetramerisation domain containing 6GDS3669
A2286 KCD12_HUMANKCTD12, PFET1BTB/POZ domain-containing protein KCTD12GDS3669
A2288 SHKB1_HUMANSHKBP1, PP203SH3KBP1-binding protein 1GDS3669
A2294 KCND1_HUMANKCND1Potassium voltage-gated channel subfamily D member 1GDS3669
A2308 KCNG4_HUMANKCNG4, KCNG3Potassium voltage-gated channel subfamily G member 4GDS3669
A230B ZMY12_HUMANZMYND12Zinc finger, MYND domain containing 12GDS3669
A2319 MICA1_HUMANMICAL1, MICAL, NICALCasL interacting moleculeGDS3669
A231C NPC1_HUMANNPC1Niemann-Pick C1 protein precursorGDS3669
A232J ZBT18_HUMANZNF238, RP58, TAZ1Zinc finger protein 238GDS3669
A2335 MYH7B_HUMANMYH7BMyosin-7BGDS3669
A2345 CLIP1_HUMANCLIP-170, CLIP1, CYLN1CAP-GLY domain-containing linker protein 1GDS3669
A2352 FYB_HUMANFYB, SLAP130FYN-binding proteinGDS3669
A235D RB8NL_HUMANRBBP8NLProtein C20orf151GDS3669
A235I S12A8_HUMANSLC12A8, CCC9Solute carrier family 12 member 8GDS3669
A238B ZBT21_HUMANZNF295, ZBTB21Zinc finger and BTB domain-containing protein 21GDS3669
A2390 GMIP_HUMANGMIPGem-interacting proteinGDS3669
A239C NRBP_HUMANNRBP1, BCON3, NRBPNuclear receptor-binding protein 1GDS3669
A2400 TAGAP_HUMANTAGAP, TAGAP1, FKSG15T-cell activation Rho GTPase activating proteinGDS3669
A2439 CENPV_HUMANCENPV, PRR6, p30Centromere protein VGDS3669
A2461 ASH1L_HUMANASH1L, KMT2HAbsent, small, or homeotic 1-likeGDS3669
A2475 PIGG_HUMANPIGG, GPI7, UNQ1930/PRO4405GPI ethanolamine phosphate transferase 2GDS3669
A248I S1PR5_HUMANS1PR5, EDG8, GPCRSphingosine 1-phosphate receptor 5GDS3669
A2493 FOSL2_HUMANFOSL2, FRA2Fos-related antigen 2GDS3669
A2496 ATF3_HUMANATF3, ATF3deltaZip2exonD'DE'E, ATF3deltaZip2aCyclic-AMP-dependent transcription factor ATF-3GDS3669
A250C NUCB1_HUMANNUCB1, NUC, CALNUCNucleobindin 1 precursorGDS3669
A250J ZCHC7_HUMANZCCHC7, HSPC086Zinc finger CCHC domain containing protein 7GDS3669
A251H MAFB_HUMANMAFB, KRMLTranscription factor MafBGDS3669
A2529 CELF2_HUMANCELF2, CUGBP2, BRUNOL3Paraneoplastic Encephalomyelitis antigen family proteinGDS3669
A252K DOT1L_HUMANDOT1L, KMT4Histone-lysine N-methyltransferase, H3 lysine-79 specificGDS3669
A253F ADR2_HUMANADIPOR2, PAQR2Adiponectin receptor protein 2GDS3669
A2581 SRS10_HUMANFUSIP1, SRSF10, FUSIP2FUS-interacting Serine-Arginine-rich protein 1GDS3669
A2607 SRBP2_HUMANSREBF2, BHLHD2, SREBP2Sterol regulatory element binding protein-2GDS3669
A2609 USF2_HUMANUSF2, BHLHB12Upstream stimulatory factor 2GDS3669
A262A BTG1_HUMANBTG1BTG1 proteinGDS3669
A2639 ZEP2_HUMANHIVEP2, MIBP1Transcription factor HIVEP2GDS3669
A264A BZW1_HUMANBZW1, BZAP45, ORFBasic leucine zipper and W2 domain-containing protein 1GDS3669
A269B ZN691_HUMANZNF691Zinc finger protein 691GDS3669
A272I S35D3_HUMANSLC35D3, FRCL1Solute carrier family 35, member D3GDS3669
A274C OSBP2_HUMANOSBP2, ORP4, OSBPL4Oxysterol-binding protein 2GDS3669
A276C PACS1_HUMANPACS1Phosphofurin acidic cluster sorting protein 1GDS3669
A279H MBNL2_HUMANMBNL2, MBLL, MBLL39Muscleblind-like protein 2GDS3669
A282H MBPHL_HUMANMYBPHLMyosin binding protein H-likeGDS3669
A285A CENPA_HUMANCENPAHistone H3-like centromeric protein AGDS3669
A285G ERP27_HUMANERP27, UNQ781/PRO1575, UNQ781Endoplasmic reticulum resident protein ERP27 precursorGDS3669
A286F ALKB1_HUMANALKBH1, ABH, ABH1Alkylated DNA repair protein alkB homolog 1GDS3669
A289J PCSK6_HUMANPCSK6, PACE4Proprotein convertase subtilisin/kexin type 6GDS3669
A290E SDCB2_HUMANSDCBP2, SITAC18Syntenin 2GDS3669
A2950 ZN778_HUMANZNF778Zinc finger protein 778GDS3669
A298J TM156_HUMANTMEM156Transmembrane protein 156GDS3669
A2998 ZKSC5_HUMANZKSCAN5, ZFP95Zinc finger protein 95 homologGDS3669
A3039 ZN467_HUMANZNF467Zinc finger protein 467GDS3669
A303F ANC2_HUMANANAPC2, APC2Anaphase promoting complex subunit 2GDS3669
A304C QCR6_HUMANUQCRHUbiquinol-cytochrome C reductase complex 11 kDa protein, mitochondrial precursorGDS3669
A309I SAC31_HUMANSAC3D1, SHD1, HSU79266SAC3 domain-containing protein 1GDS3669
A3103 SP3_HUMANSP3Transcription factor Sp3GDS3669
A310F ANKR9_HUMANANKRD9Ankyrin repeat domain-containing protein 9GDS3669
A310H MED31_HUMANMED31, SOH1, CGI-125Mediator of RNA polymerase II transcription subunit 31GDS3669
A313G F117B_HUMANFAM117B, ALS2CR13Protein FAM117BGDS3669
A314E SH3L2_HUMANSH3BGRL2, FASH3SH3 domain binding glutamic acid-rich protein like 2GDS3669
A315I SAM14_HUMANSAMD14Sterile alpha motif domain-containing protein 14GDS3669
A3160 KAT6A_HUMANKAT6A, MYST3, MOZHistone acetyltransferase MYST3GDS3669
A3166 MYH9_HUMANMYH9Myosin heavy chain 9, non-muscleGDS3669
A317F ANO8_HUMANANO8, TMEM16HAnoctamin-8GDS3669
A317K SPOC1_HUMANSPOCD1SPOC domain-containing protein 1GDS3669
A3180 PHC3_HUMANPHC3, EDR3, PH3Polyhomeotic-like protein 3GDS3669
A319A CRNL1_HUMANCRNKL1, crn, CRNCrooked neck pre-mRNA splicing factor-like 1GDS3669
A3206 IKIP_HUMANIKBIP, IKIP, IKIP2Inhibitor of nuclear factor kappa-B kinase-interacting proteinGDS3669
A3243 ZN652_HUMANZNF652Zinc finger protein 652GDS3669
A3254 ZBT24_HUMANZBTB24, ZNF450Zinc finger protein 450GDS3669
A325H MET22_HUMANMETTL22, LP8272Uncharacterized protein C16ORF68GDS3669
A3267 BCL6_HUMANBCL6, ZNF, BCL5B-cell lymphoma 6 proteinGDS3669
A326K ZN703_HUMANZNF703, ZEPPO1, ZPO1Zinc finger protein 703GDS3669
A3272 ZN580_HUMANZNF580Zinc finger protein 580GDS3669
A327J ZN513_HUMANZNF513Zinc finger protein 513GDS3669
A3339 ARP3B_HUMANACTR3B, ARP4, ARP3BETAActin-related protein 3BGDS3669
A333D EPG5_HUMANEPG5UPF0493 protein KIAA1632GDS3669
A336H MFA3L_HUMANMFAP3L, HSD39, HSD-39Microfibrillar-associated protein 3-like precursorGDS3669
A339G F16B1_HUMANFAM160B1UPF0518 protein FAM160B1GDS3669
A339H MFNG_HUMANMFNGBeta-1,3-N-acetylglucosaminyltransferase manic fringeGDS3669
A339I SC5D_HUMANSC5DLLathosterol oxidaseGDS3669
A342I SC6A4_HUMANSLC6A4, 5HTT, HTTSodium-dependent serotonin transporterGDS3669
A343I SC6A6_HUMANSLC6A6Sodium- and chloride-dependent taurine transporterGDS3669
A3464 PGRC1_HUMANPGRMC1, HPR6.6, PGRMCMembrane associated progesterone receptor component 1GDS3669
A3496 FLOT1_HUMANFLOT1Flotillin-1GDS3669
A3503 MINK1_HUMANMINK, MINK1, MAP4K6Misshapen-like kinase 1GDS3669
A3511 RMD3_HUMANRMDN3, FAM82A2, FAM82CRegulator of microtubule dynamics protein 3GDS3669
A3518 SEPT5_HUMANSep-05, CDCrel-1, PNUTL1Septin 5GDS3669
A3520 SEPT7_HUMANSep-07, CDC10Septin-7GDS3669
A3557 NOE1_HUMANOLFM1, NOE1, NOEL1Noelin precursorGDS3669
A357H MK07_HUMANMAPK7, BMK1, ERK5Mitogen-activated protein kinase 7GDS3669
A3582 ACACA_HUMANACACA, ACAC, ACC1Acetyl-CoA carboxylase 1GDS3669
A3584 FAS_HUMANFASN, FASFatty acid synthaseGDS3669
A358C S52A2_HUMANSLC52A2, GPR172A, GPCRPorcine endogenous retrovirus A receptor 1 precursorGDS3669
A3591 PI51C_HUMANPIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type I gammaGDS3669
A3593 ACBG1_HUMANACSBG1, BGM, LPDVery long-chain acyl-CoA synthetase, lipidosinGDS3669
A3615 ENOA_HUMANENO1, ENO1L1, MBPB1Alpha enolaseGDS3669
A3632 LPP3_HUMANPPAP2B, LPP3, DRI42Lipid phosphate phosphohydrolase 3GDS3669
A364D ZC21A_HUMANZC2HC1A, FAM164A, CGI-62Protein FAM164AGDS3669
A3650 SGPP1_HUMANSGPP1Sphingosine-1-phosphate phosphatase 1GDS3669
A370A EFTU_HUMANTUFMElongation factor Tu, mitochondrial precursorGDS3669
A371I SENP7_HUMANSENP7, SSP2, SUSP2Sentrin-specific protease 7GDS3669
A373E M3KCL_HUMANMAP3K7CL, HC21ORF7, TAK1LMAP3K7 C-terminal-like proteinGDS3669
A373F ARL4A_HUMANARL4A, ARL4ADP-ribosylation factor-like protein 4GDS3669
A373H MO2R1_HUMANCD200R1, CD200R, CRTR2Cell surface glycoprotein CD200 receptor 1GDS3669
A3745 MCAT_HUMANSLC25A20, CAC, CACTMitochondrial carnitine/acylcarnitine carrier proteinGDS3669
A374F ARL5A_HUMANARL5A, ARFLP5, ARL5ADP-ribosylation factor-like protein 5AGDS3669
A3757 GDC_HUMANSLC25A16, GDAGrave's disease carrier proteinGDS3669
A376E TBC23_HUMANTBC1D23, NS4ATP1TBC1 domain family member 23GDS3669
A376I SESN1_HUMANSESN1, PA26, SEST1Sestrin 1GDS3669
A377A EIF3C_HUMANEIF3C, EIF3S8Eukaryotic translation initiation factor 3 subunit CGDS3669
A3816 RS3_HUMANRPS340S ribosomal protein S3GDS3669
A381F ARMX6_HUMANARMCX6Armadillo repeat containing, X-linked 6GDS3669
A381I SETD4_HUMANSETD4SET domain-containing protein 4GDS3669
A3824XK1C10_HUMANKRT10, KPPKeratin, type I cytoskeletal 10GDS3669
A383B CKLF5_HUMANCMTM5, CKLFSF5CKLF-like Marvel transmembrane domain-containing protein 5GDS3669
A3851 K2C75_HUMANKRT75, K6HF, KB18Keratin, type II cytoskeletal 75GDS3669
A386I SFR1_HUMANSFR1, MEI5, MEIR5Hypothetical proteinGDS3669
A3876 ADDA_HUMANADD1, ADDAAlpha adducinGDS3669
A390I SG1C1_HUMANSCGB1C1, RYD5Secretoglobin family 1C member 1 precursorGDS3669
A3916 NPS3A_HUMANNIPSNAP3A, NIPSNAP4, HSPC299NipSnap4 proteinGDS3669
A3951 SFXN1_HUMANSFXN1Sideroflexin 1GDS3669
A3956 MTX1_HUMANMTX1, MTX, MTXNMetaxin 1GDS3669
A3969 DCTN4_HUMANDCTN4Dynactin 4GDS3669
A3974 MIRO1_HUMANRHOT1, ARHT1, MIRO-1Mitochondrial RHO GTPase 1GDS3669
A3978 CHIP_HUMANSTUB1, CHIP, PP1131STIP1 homology and U box-containing protein 1GDS3669
A399H MPIP1_HUMANCDC25ACell division cycle 25AGDS3669
A4006 EFR3A_HUMANEFR3AProtein EFR3 homolog AGDS3669
A4021 TIM8B_HUMANTIMM8B, DDP2, DDPLTranslocase of inner mitochondrial membrane 8 homolog BGDS3669
A4023 MCU_HUMANMCU, CCDC109ACalcium uniporter protein, mitochondrialGDS3669
A4037 KAPCB_HUMANPRKACB, PKACBcAMP-dependent protein kinase, beta-catalytic subunitGDS3669
A4050 S22A5_HUMANSLC22A5, OCTN2VT, OCTN2Organic cation/carnitine transporter 2GDS3669
A4060 ASPM_HUMANASPM, MCPH5Abnormal spindlesGDS3669
A406H MPRG_HUMANPAQR5, MPRGMembrane Progestin receptor gammaGDS3669
A4080 CCYL1_HUMANCCNYL1Cyclin-Y-like protein 1GDS3669
A4108 DLGP5_HUMANDLGAP5, DLG7Disks large-associated protein 5GDS3669
A4119 FANCF_HUMANFANCFFanconi anemia group F proteinGDS3669
A411A EXOS3_HUMANEXOSC3, PNAS-3, RRP40Exosome complex exonuclease RRP40GDS3669
A4123 G0S2_HUMANG0S2G0/G1 switch regulatory protein 2GDS3669
A413C S26A1_HUMANSLC26A1, SAT1Sulfate anion transporter 1GDS3669
A415F ASND1_HUMANASNSD1, NS3TP1Asparagine synthetase domain-containing protein 1GDS3669
A415I SI1L2_HUMANSIPA1L2Signal-induced proliferation-associated 1-like protein 2GDS3669
A416C S26A6_HUMANSLC26A6Solute carrier family 26 member 6GDS3669
A419B DEN4C_HUMANDENND4CDENN domain-containing protein 4C GDS3669
A420A FA96A_HUMANFAM96AUPF0195 protein FAM96AGDS3669
A420H MS18B_HUMANOIP5, MIS18BOpa-interacting protein 5GDS3669
A4267 ABCE1_HUMANABCE1, RLI, RNASEL1ATP-binding cassette sub-family E member 1GDS3669
A426I SIK1_HUMANSIK1, SIK, SNF1LKSerine/threonine-protein kinase SIK1GDS3669
A4270 AN13C_HUMANANKRD13CAnkyrin repeat domain-containing protein 13CGDS3669
A4299 DJC25_HUMANDNAJC25DnaJ homolog subfamily C member 25GDS3669
A429I SIM13_HUMANSMIM13Hypothetical protein LOC221710GDS3669
A4304 DNJB1_HUMANDNAJB1, DNAJ1, HDJ1DnaJ homolog subfamily B member 1GDS3669
A430H MSMO1_HUMANSC4MOL, MSMO1, DESP4C-4 methyl sterol oxidaseGDS3669
A431E TTC17_HUMANTTC17, HSPC313Tetratricopeptide repeat protein 17GDS3669
A4337 HSBP1_HUMANHSBP1, HSF1BP, NPC-A-13Heat shock factor binding protein 1GDS3669
A4346 HSPB3_HUMANHSPB3, HSPL27, HSP27Heat-shock protein, beta-3GDS3669
A436A FOXN2_HUMANFOXN2, HTLFHuman T-cell leukemia virus enhancer factorGDS3669
A4378 PSD10_HUMANPSMD10Proteasome (prosome, macropain) 26S subunit, non-ATPase, 10GDS3669
A438D FA76B_HUMANFAM76BProtein FAM76BGDS3669
A441B EVA1B_HUMANEVA1B, FAM176BTransmembrane protein C1ORF78GDS3669
A442I SIX5_HUMANSIX5, DMAHPHomeobox protein SIX5GDS3669
A4458 CXD4_HUMANGJD4, CX40.1Connexin40.1GDS3669
A4476 KCNE3_HUMANKCNE3Potassium voltage-gated channel subfamily E member 3GDS3669
A448E TTL12_HUMANTTLL12Tubulin-tyrosine ligase-like protein 12GDS3669
A450I SL9A9_HUMANSLC9A9, NHE9Sodium/hydrogen exchanger 9GDS3669
A452F B3GN5_HUMANB3GNT5, BETA3GNT5UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5GDS3669
A4538 TRPV5_HUMANECAC1, TRPV5Transient receptor potential cation channel, subfamily V, member 5GDS3669
A455B FA69A_HUMANFAM69ASimilar to RIKEN cDNA 2900024C23GDS3669
A455I SLAF9_HUMANSLAMF9, CD2F10, UNQ1938/PRO4421SLAM family member 9GDS3669
A456H MTR1B_HUMANMTNR1BMelatonin receptor type 1BGDS3669
A4570 ANTR1_HUMANANTXR1, ATR, TEM8Anthrax toxin receptor 1 precursorGDS3669
A4571 ANTR2_HUMANANTXR2, CMG2Anthrax toxin receptor 2GDS3669
A4576 ANXA5_HUMANANXA5, ANX5, ENX2Annexin A5GDS3669
A4603 BRK1_HUMANBRK1, HSPC300, MDS027Probable protein BRICK1GDS3669
A460H MYBA_HUMANMYBL1, A-myb, AMYBMyb-related protein AGDS3669
A461C SAR1B_HUMANSAR1B, SARA2, SARBGTP-binding protein SAR1bGDS3669
A4629 CALD1_HUMANCALD1, CAD, CDMCaldesmonGDS3669
A4641 CD151_HUMANCD151, TSPAN24Platelet-endothelial tetraspan antigen 3GDS3669
A4643 CD22_HUMANCD22, SIGLEC2B-cell receptor CD22 precursorGDS3669
A4645 CD33_HUMANCD33, SIGLEC3Myeloid cell surface antigen CD33 precursorGDS3669
A4661 CE350_HUMANCEP350, CAP350, GM133Centrosomal protein 350kDaGDS3669
A4678 CHAD_HUMANCHAD, SLRR4AChondroadherin precursorGDS3669
A467B GBP7_HUMANGBP7, GBP4L, GBP2Guanylate-binding protein 7GDS3669
A467E UBXN6_HUMANUBXN6, UBXD1, UBXDC2UBX domain-containing protein 1GDS3669
A467G FLI1_HUMANFLI1Friend leukemia integration 1 transcription factorGDS3669
A469G FLVC2_HUMANFLVCR2Feline leukemia virus subgroup C receptor-related protein 2GDS3669
A471H MYOV2_HUMANMYEOV2Myeloma overexpressed gene 2 proteinGDS3669
A472C SC24C_HUMANSEC24CProtein transport protein Sec24CGDS3669
A4744 DAG1_HUMANDAG1Dystroglycan precursorGDS3669
A4746 DC1L2_HUMANDYNC1LI2, DNCLI2, LIC2Dynein light intermediate chain 2, cytosolicGDS3669
A475A H1T_HUMANHIST1H1T, H1FT, H1THistone H1TGDS3669
A475I SMI19_HUMANSMIM19UPF0697 protein C8ORF40GDS3669
A477A H2A1_HUMANHIST1H2AG, H2AFP, HIST1H2AIHistone H2A type 1GDS3669
A477G FOLC_HUMANFPGSFolylpolyglutamate synthase, mitochondrial precursorGDS3669
A478B GSLG1_HUMANGLG1, CFR1, ESL1Golgi apparatus protein 1 precursorGDS3669
A478K KBTB6_HUMANKBTBD6KELCH repeat and BTB domain-containing protein 6GDS3669
A480I SMOX_HUMANSMOX, SMO, UNQ3039/PRO9854Spermine oxidaseGDS3669
A4821 FOPNL_HUMANFOPNL, FOR20, PHSECRG2Lissencephaly type-1-like homology motif domain containing proteinGDS3669
A4867 INF2_HUMANINF2, pp9484, PP9484Inverted formin 2GDS3669
A491H NANP_HUMANNANP, HDHD4N-acylneuraminate-9-phosphataseGDS3669
A493A H2AX_HUMANH2AFX, H2AXHistone H2A.xGDS3669
A4942 LIMA1_HUMANLIMA1, EPLIN, SREBP3LIM domain and actin-binding protein 1GDS3669
A4975 MLP3A_HUMANMAP1LC3AMAP1 light chain 3-like protein 1GDS3669
A498CXSEPP1_HUMANSEPP1, SELPSelenoprotein P precursorGDS3669
A499A H2B1C_HUMANHIST1H2BC, HIST1H2BE, HIST1H2BFHistone H2B.a/g/h/kGDS3669
A499C SERP1_HUMANSERP1, RAMP4Stress-associated endoplasmic reticulum protein 1GDS3669
A5003 MZT2B_HUMANMZT2B, FAM128B, MOZART2BProtein FAM128BGDS3669
A5009 NIN_HUMANNIN, NINEINNineinGDS3669
A5013 NPHP4_HUMANNPHP4Nephrocystin 4GDS3669
A502A H2B1H_HUMANHIST1H2BH, H2BFJHistone H2B type 1-HGDS3669
A510C SNP23_HUMANSNAP23, SNAP-23Synaptosomal-associated protein 23GDS3669
A513A H2B2E_HUMANHIST2H2BE, H2BFQ, H2B.1Histone H2B type 2-EGDS3669
A513C SNX11_HUMANSNX11Sorting nexin 11GDS3669
A5140 SPON2_HUMANSPON2, DIL1, UNQ435/PRO866Spondin 2GDS3669
A514B LRC8D_HUMANLRRC8D, LRRC5, UNQ213/PRO239Leucine-rich repeat-containing 8 family, member DGDS3669
A5151 SPTN1_HUMANSPTAN1, SPTA2, NEASSpectrin alpha chain, brainGDS3669
A5152 SPTB1_HUMANHSpTB1, SPTB, SPTB1Spectrin beta chain, erythrocyteGDS3669
A515C SNX13_HUMANSNX13Sorting nexin 13GDS3669
A515F BN3D2_HUMANBCDIN3DProbable methyltransferase BCDIN3DGDS3669
A5176 TB15A_HUMANTMSB15A, TMSL8, TMSNBThymosin beta-15AGDS3669
A5188 TBB1_HUMANTUBB1TUBB1 human beta tubulin 1, class VIGDS3669
A518B LRMP_HUMANLRMP, JAW1Lymphoid-restricted membrane proteinGDS3669
A519A H32_HUMANHIST2H3A, HIST2H3C, H3F2Histone H3.2GDS3669
A520A H33_HUMANH3F3A, H3F3B, H3.3AH3 histone, family 3AGDS3669
A520F BORG2_HUMANCDC42EP3, BORG2, CEP3CDC42 effector protein 3GDS3669
A520K BBIP1_HUMANBBIP1, BBIP10BBsome-interacting protein of 10 kDaGDS3669
A5217 TMOD3_HUMANTMOD3Ubiquitous tropomodulinGDS3669
A5220 TOIP1_HUMANTOR1AIP1, LAP1BTorsin-1A-interacting protein 1GDS3669
A522B LYSM3_HUMANLYSMD3LYSM and putative peptidoglycan-binding domain-containing protein 3GDS3669
A523D GVIN1_HUMANGVINP1, GVIN1Interferon-inducible very large GTPase 1GDS3669
A5242 VILI_HUMANVIL1, VILVillin 1GDS3669
A526C SNX5_HUMANSNX5Sorting nexin 5GDS3669
A5314 DLK1_HUMANDLK1, DLK, FA1Protein delta homolog 1GDS3669
A532B MEGF9_HUMANMEGF9, EGFL5, UNQ671/PRO1305Multiple epidermal growth factor-like domains protein 9 precursorGDS3669
A533B MENTO_HUMANSTARD3NL, MENTHO, UNQ855/PRO1864MLN64 N-terminal domain homologGDS3669
A5345 GMCL1_HUMANGMCL1, GCLGerm cell-less protein-like 1GDS3669
A5355 HOP_HUMANHOPX, HOD, HOPHomeodomain-only proteinGDS3669
A5361 IFRD1_HUMANIFRD1Interferon-related developmental regulator 1GDS3669
A536E YTHD3_HUMANYTHDF3YTH domain family protein 3GDS3669
A538J PTAR1_HUMANPTAR1Protein prenyltransferase alpha subunit repeat containing 1GDS3669
A5416 NP1L1_HUMANNAP1L1, NRPNucleosome assembly protein 1-like 1GDS3669
A5418 NP1L4_HUMANNAP1L4, NAP1L4b, NAP2Nucleosome assembly protein 1-like 4GDS3669
A542C SPN1_HUMANSNUPN, RNUT1, SPN1Snurportin1GDS3669
A542D MROH1_HUMANMROH1, HEATR7AMaestro heat-like repeat-containing protein family member 1GDS3669
A5434 PLIN2_HUMANADFP, PLIN2AdipophilinGDS3669
A545J RBM6_HUMANRBM6, DEF3, NY-LU-12RNA-binding protein 6GDS3669
A546E MEF2D_HUMANMEF2DMyocyte-specific enhancer factor 2DGDS3669
A5486 STX2_HUMANEPIM, STX2, STX2AEpimorphinGDS3669
A5489 T176B_HUMANTMEM176B, LR8Transmembrane protein 176BGDS3669
A5509 VEGFC_HUMANVEGFCVascular endothelial growth factor C precursorGDS3669
A550B NSG1_HUMAND4S234E, NSG1, D4S234Neuron specific protein family member 1GDS3669
A552G GAPT_HUMANGAPTHypothetical protein GDS3669
A5542 CTGE5_HUMANCTAGE5, MEA11, MEA6Cutaneous T-cell lymphoma-associated antigen 5GDS3669
A555B OSTC_HUMANOSTC, DC2, HDCMD45POligosaccharyltransferase complex subunit OSTCGDS3669
A5568 NDUF3_HUMANNDUFAF3NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3GDS3669
A557J ZFY16_HUMANZFYVE16EndofinGDS3669
A558J ZN800_HUMANZNF800, PP902Zinc finger protein 800GDS3669
A5600 TAZ_HUMANTAZ, EFE2, G4.5TafazzinGDS3669
A562B PCX1_HUMANPCNX, PCNXL1Pecanex-like protein 1GDS3669
A564B PDZ1I_HUMANPDZK1IP1, MAP17PDZK1-interacting protein 1GDS3669
A564G GBA2_HUMANGBA2Non-lysosomal glucosylceramidaseGDS3669
A5657 ACADV_HUMANACADVL, VLCADAcyl-CoA dehydrogenase, very-long-chain specific, mitochondrial precursorGDS3669
A565G GBGT1_HUMANGBGT1, UNQ2513/PRO6002, FSGloboside alpha-1,3-N-acetylgalactosaminyltransferase 1GDS3669
A5669 ACO13_HUMANACOT13, THEM2, HT012Acyl-coenzyme A thioesterase 13GDS3669
A5693 ACSL1_HUMANACSL1, FACL1, FACL2Long-chain-fatty-acid--CoA ligase 1GDS3669
A5701 ACV1B_HUMANACVR1B, ACVRLK4, ALK4Activin receptor type-1BGDS3669
A5721 ADCK3_HUMANCABC1, ADCK3, PP265Chaperone-activity of bc1 complex-like, mitochondrial precursorGDS3669
A5763 AL3A2_HUMANALDH3A2, ALDH10, FALDHFatty aldehyde dehydrogenaseGDS3669
A5777 ALG5_HUMANALG5, HSPC149Dolichyl-phosphate beta-glucosyltransferaseGDS3669
A5794 AMPD2_HUMANAMPD2AMP deaminase 2GDS3669
A579H NP1L5_HUMANNAP1L5, DRLMNucleosome assembly protein 1-like 5GDS3669
A579I SSBP3_HUMANSSBP3, SSDP, SSDP1Single-stranded DNA-binding protein 3GDS3669
A5815 APEX1_HUMANAPEX1, APE, APEXDNA-(apurinic or apyrimidinic site) lyaseGDS3669
A581A IF2P_HUMANEIF5B, IF2Eukaryotic translation initiation factor 5BGDS3669
A5827 ARLY_HUMANASL, LP3236Argininosuccinate lyaseGDS3669
A5835 ASM3A_HUMANSMPDL3A, ASML3A, ASM3AAcid sphingomyelinase-like phosphodiesterase 3AGDS3669
A5849 AT131_HUMANATP13A1, ATP13A, CGI-152Probable cation-transporting ATPase 2GDS3669
A5861 AT8B4_HUMANATP8B4Potential phospholipid-transporting ATPase IMGDS3669
A586G GEMI6_HUMANGEMIN6Gem-associated protein 6GDS3669
A5908 EXD2_HUMANEXD2, EXDL2Exonuclease 3'-5' domain containing protein 2GDS3669
A591B RRNAD_HUMANRRNAD1, CGI-41Hypothetical proteinGDS3669
A5922 BCKD_HUMANBCKDK[3-methyl-2-oxobutanoate] dehydrogenase [lipoamide] kinase, mitochondrial precursorGDS3669
A5928 BIEA_HUMANBLVRA, BLVR, BVRBiliverdin reductase A precursorGDS3669
A594G GI24_HUMANSISP1, PP2135, UNQ730/PRO1412Platelet receptor GI24 precursorGDS3669
A5967 CAH5A_HUMANCA5A, CA5Carbonic anhydrase 5AGDS3669
A5969 CAH6_HUMANCA6Carbonic anhydrase VI precursorGDS3669
A5983 CATC_HUMANCTSC, CPPIDipeptidyl-peptidase 1 precursorGDS3669
A5984 CATD_HUMANCTSD, CPSDCathepsin D precursorGDS3669
A5989 CATL1_HUMANCTSL1, CTSL, MEPCathepsin L1 precursorGDS3669
A598B SERC2_HUMANSERINC2, TDE2L, FKSG84Serine incorporator 2GDS3669
A599I STING_HUMANMITA, TMEM173, ERISStimulator of interferon genes proteinGDS3669
A6003 CBPD_HUMANCPDCarboxypeptidase D precursorGDS3669
A6034 CDS2_HUMANCDS2Phosphatidate cytidylyltransferase 2GDS3669
A604F CASC4_HUMANCASC4, UNQ2573/PRO6308, H63Cancer susceptibility candidate 4GDS3669
A6054 CHPF2_HUMANCHPF2, CSGlcA-T, CHSY3Chondroitin sulfate glucuronyltransferaseGDS3669
A6067 CHSTB_HUMANCHST11, C4ST, C4S-1ACarbohydrate sulfotransferase 11GDS3669
A606H NR4A1_HUMANNR4A1, GFRP1, HMRNuclear receptor subfamily 4, group A, member 1GDS3669
A607G GLCI1_HUMANGLCCI1Glucocorticoid induced transcript 1 proteinGDS3669
A607H NR4A2_HUMANNR4A2, NOT, NURR1Nuclear receptor subfamily 4, Group A, member 2GDS3669
A6092 COMT_HUMANCOMTCatechol O-methyltransferase, membrane-bound formGDS3669
A6093 COQ2_HUMANCOQ2, CL640Para-hydroxybenzoate-polyprenyltransferase, mitochondrialGDS3669
A612A INT7_HUMANINTS7Integrator complex subunit 7GDS3669
A6195 CP51A_HUMANCYP51A1, CYP51Cytochrome P450, family 51, subfamily A, polypeptide 1GDS3669
A6200 CPPED_HUMANCPPED1, CSTP1Calcineurin-like phosphoesterase domain-containing protein 1GDS3669
A621C TMED2_HUMANTMED2, RNP24Transmembrane EMP24 domain-containing protein 2 precursorGDS3669
A6226 CTSL2_HUMANCTDSPL2, HSPC058, HSPC129CTD small phosphatase-like protein 2GDS3669
A6227 CX6A1_HUMANCOX6A1, COX6AL, RP3-405J24.3Cytochrome c oxidase subunit 6A1, mitochondrial precursorGDS3669
A6231 CX7A2_HUMANCOX7A2, COX7ALCytochrome C oxidase polypeptide VIIa-liver/heart, mitochondrial precursorGDS3669
A625C TMX1_HUMANTXNDC, TMX1, TMXThioredoxin-related transmembrane protein 1GDS3669
A6267 DDX21_HUMANDDX21Nucleolar RNA helicase 2GDS3669
A6270 DDX25_HUMANDDX25, GRTHATP-dependent RNA helicase DDX25GDS3669
A6286 DDX58_HUMANDDX58, RIG-IProbable ATP-dependent RNA helicase DDX58GDS3669
A629A KI67_HUMANMKI67Antigen KI-67GDS3669
A6307 DHB3_HUMANHSD17B3, EDH17B3Estradiol 17 beta-dehydrogenase 3GDS3669
A6312 DHC24_HUMANDHCR2424-dehydrocholesterol reductase precursorGDS3669
A631D KLH10_HUMANKLHL10KELCH-like 10GDS3669
A6339 DKC1_HUMANdkc1, DKC1, NOLA4DyskerinGDS3669
A634G GP141_HUMANGPR141, PGR13G protein-coupled receptor 141GDS3669
A636F CC062_HUMAN Uncharacterized protein C3ORF62GDS3669
A6380 DUS1_HUMANDUSP1, CL100, MKP1Dual specificity protein phosphatase 1GDS3669
A638A LCORL_HUMANLCORL, MLR1Ligand-dependent nuclear receptor corepressor-like proteinGDS3669
A6392 DUS3_HUMANDUSP3, VHRDual specificity protein phosphatase 3GDS3669
A6403 EBP_HUMANEBP3-beta-hydroxysteroid-delta(8),delta(7)-isomeraseGDS3669
A6416 EGLN3_HUMANEGLN3Egl nine homolog 3GDS3669
A6440 ERG1_HUMANERG1, SQLESqualene monooxygenaseGDS3669
A644I T150A_HUMANTMEM150A, TMEM150, TM6P1Transmembrane protein 150AGDS3669
A645G GP171_HUMANGPR171, H963Probable G-protein coupled receptor 171GDS3669
A6474 EYA3_HUMANEYA3Eyes absent homolog 3GDS3669
A6481 F263_HUMANPFKFB3, PFK2, IPFK26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3GDS3669
A6483 FAAA_HUMANFAHFumarylacetoacetaseGDS3669
A6487 FACE1_HUMANZMPSTE24, FACE1, STE24CAAX prenyl protease 1 homologGDS3669
A648B CTSRD_HUMANCATSPERD, TMEM146Cation channel sperm-associated protein subunit deltaGDS3669
A6492 FADS1_HUMANFADS1, FADSD5, FADS3Fatty acid desaturase 1GDS3669
A6493 FADS2_HUMANFADS2, P5327Delta-6 fatty acid desaturaseGDS3669
A649G GP183_HUMANGPR183, EBI2G-protein coupled receptor 183GDS3669
A6504 FDFT_HUMANFDFT1Farnesyl-diphosphate farnesyltransferase 1GDS3669
A6522 FPPS_HUMANFDPS, FPSFarnesyl diphosphate synthaseGDS3669
A6524 FRIH_HUMANFTH1, FTH, FTHL6Ferritin heavy chainGDS3669
A653H NXT2_HUMANNXT2, BM-025, DC9NTF2-related export protein 2GDS3669
A6554 GAK_HUMANGAKCyclin G-associated kinaseGDS3669
A655C UBQL4_HUMANUBQLN4, UBIN, A1UUbiquilin-4GDS3669
A6572 GATM_HUMANGATM, AGATGlycine amidinotransferase, mitochondrial precursorGDS3669
A6605XGLPK_HUMANGKGlycerol kinaseGDS3669
A662A LYAR_HUMANLYAR, PNAS-5Cell growth-regulating nucleolar proteinGDS3669
A662F CC85B_HUMANCCDC85B, DIPADelta-interacting protein AGDS3669
A663A MAEL_HUMANMAELProtein Maelstrom homologGDS3669
A664A MAF1_HUMANMAF1Repressor of RNA polymerase III transcription MAF1 homologGDS3669
A6664 GSHR_HUMANGSR, GLUR, GRD1Glutathione reductase, mitochondrial precursorGDS3669
A6666 GSTA2_HUMANGSTA2, GST2Glutathione S-transferase A2GDS3669
A6673 GTDC1_HUMANGTDC1, Hmat-XaGycosyltransferase-like domain-containing protein 1GDS3669
A6685 HACD3_HUMANPTPLAD1, BIND1, HACD3Protein tyrosine phosphatase-like protein PTPLAD1GDS3669
A6704 HECD3_HUMANHECTD3Probable E3 ubiquitin-protein ligase HECTD3GDS3669
A670A MBD2_HUMANNY-CO-41, MBD2Methyl-CpG binding protein 2GDS3669
A6717 HERC1_HUMANHERC1Probable E3 ubiquitin-protein ligase HERC1GDS3669
A671A MBD3_HUMANMBD3Methyl-CpG binding protein MBD3GDS3669
A6732 HMCS1_HUMANHMGCS1, HMGCSHydroxymethylglutaryl-CoA synthase, cytoplasmicGDS3669
A6737 HNMT_HUMANHNMT, HMTHistamine N-methyltransferaseGDS3669
A673A MBD6_HUMANMBD6Methyl-CpG binding domain protein 6GDS3669
A673C VAMP7_HUMANVAMP7, SYBL1, SYBL1BVesicle-associated membrane protein 7GDS3669
A673H OGRL1_HUMANOGFRL1Opioid growth factor receptor-like protein 1GDS3669
A6753 HTRA2_HUMANHTRA2, OMI, PRSS25Serine protease HTRA2, mitochondrial precursorGDS3669
A675H ONCM_HUMANOSMOncostatin M precursorGDS3669
A6777 IDI1_HUMANIDI1Isopentenyl-diphosphate delta-isomerase 1GDS3669
A6778 IDUA_HUMANIDUAAlpha-L-iduronidase precursorGDS3669
A678I TA2R_HUMANTBXA2RThromboxane A2 receptorGDS3669
A6792 IMPA1_HUMANIMPA1, IMPAInositol(myo)-1(or 4)-monophosphatase 1GDS3669
A6806 IRAK3_HUMANIRAK3Interleukin-1 receptor-associated kinase 3GDS3669
A6835 KC1G2_HUMANCSNK1G2, CK1G2, CSNK1G3Casein kinase I, gamma 2 isoformGDS3669
A6839 KCC1D_HUMANCAMK1D, CAMKID, CKLIK BETACalcium/calmodulin-dependent protein kinase type 1DGDS3669
A684C VMAT2_HUMANSLC18A2, VMAT2, SVMTSynaptic vesicular amine transporterGDS3669
A685H OPSB_HUMANOPN1SW, BCPOpsin 1 (cone pigments), short-wave-sensitiveGDS3669
A687B LFG3_HUMANTMBIM1, RECS1, PP1201Transmembrane BAX inhibitor motif-containing protein 1GDS3669
A6881 LATS2_HUMANLATS2, KPM, HSLATS2Serine/threonine kinase LATS2GDS3669
A692A MED25_HUMANMED25, ACID1, ARC92Mediator of RNA polymerase II transcription subunit 25GDS3669
A6932 LYPA1_HUMANLYPLA1, APT1, LPL1Acyl-protein thioesterase-1GDS3669
A6947 MA1A2_HUMANMAN1A2, MAN1BMannosyl-oligosaccharide 1,2-alpha-mannosidase IBGDS3669
A696B TMCC2_HUMANTMCC2, hucep-11, HUCEP11Transmembrane and coiled-coil domains protein 2GDS3669
A6973 MAST4_HUMANMAST4Microtubule-associated serine/threonine-protein kinase 4GDS3669
A6977 MBOA5_HUMANLPCAT3, MBOAT5, OACT5Lysophospholipid acyltransferase 5GDS3669
A699H OSTM1_HUMANOSTM1, GL, HSPC019Osteoporosis-associated transmembrane protein 1 precursorGDS3669
A7005 MET18_HUMANMETTL18, ASTP2UPF0558 protein C1ORF156GDS3669
A700A MEF2C_HUMANMEF2CMyocyte-specific enhancer factor 2CGDS3669
A700B TMED5_HUMANTMED5, CGI-100, UNQ397/PRO733Transmembrane EMP24 protein transport domain containing 5GDS3669
A700G GRHL1_HUMANGRHL1, LBP32, MGRGrainyhead-like protein 1 homologGDS3669
A7010 METK2_HUMANMAT2A, AMS2, MATA2S-adenosylmethionine synthetase gamma formGDS3669
A7021 MGT4B_HUMANMGAT4B, UNQ906/PRO1927, UNQ906Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase BGDS3669
A7025 MIB1_HUMANMIB1, DIP1, ZZANK2E3 ubiquitin-protein ligase MIB1GDS3669
A7035 KMT2A_HUMANMLL, ALL1, CXXC7Histone-lysine N-methyltransferase MLLGDS3669
A703G GRK6_HUMANGRK6, GPRK6G protein-coupled receptor kinase GRK6GDS3669
A7061 MRCKG_HUMANCDC42BPG, HSMDPKIN, DMPK2Serine/threonine-protein kinase MRCK gammaGDS3669
A708A MIER1_HUMANMIER1, MI-ER1Mesoderm induction early response 1 homologGDS3669
A708B TMM27_HUMANTMEM27, UNQ679/PRO1312, NX17Collectrin precursorGDS3669
A708H OTUL_HUMANFAM105BConserved hypothetical proteinGDS3669
A7093 MVD1_HUMANMVD, MPD, FP17780Diphosphomevalonate decarboxylaseGDS3669
A709A MIER3_HUMANMIER3Mesoderm induction early response protein 3GDS3669
A7107 NAGPA_HUMANNAGPAN-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidaseGDS3669
A710B TMM40_HUMANTMEM40Transmembrane protein 40GDS3669
A7110 NAMPT_HUMANNAMPT, NAMPTL, PBEFNicotinamide phosphoribosyltransferaseGDS3669
A7125 NCOA3_HUMANNCOA3, AIB1, BHLHE42Nuclear receptor coactivator 3GDS3669
A712F CD37L_HUMANCDC37L1, CDC37B, HARCHSP90 co-chaperone CDC37-like 1GDS3669
A7136 NDST2_HUMANNDST2, HSST2Bifunctional heparan sulfate N-deacetylase/N sulfotransferase 2GDS3669
A7165 NMT2_HUMANNMT2Glycylpeptide N-tetradecanoyltransferase 2GDS3669
A7174 NQO1_HUMANNQO1, DIA4, NMOR1NAD(P)H dehydrogenase [quinone] 1GDS3669
A7179 NSDHL_HUMANNSDHL, H105E3NAD(P)-dependent steroid dehydrogenaseGDS3669
A7182 NSMA3_HUMANSMPD4Sphingomyelin phosphodiesterase 4GDS3669
A718B TMTC3_HUMANTMTC3, SMILETransmembrane and TPR repeat-containing protein 3GDS3669
A720D MLKL_HUMANMLKLMixed lineage kinase domain-like proteinGDS3669
A720F CD69_HUMANCD69, CLEC2CEarly activation antigen CD69GDS3669
A7225 OCRL_HUMANOCRL, OCRL-1, INPP5FInositol polyphosphate 5-phosphatase OCRL-1GDS3669
A723C ZNT1_HUMANSLC30A1, ZNT1Zinc transporter 1GDS3669
A7252 P3C2A_HUMANPIK3C2APhosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptideGDS3669
A725H P3_HUMANSLC10A3, DXS253E, P3Solute carrier family 10 (sodium/bile acid cotransporter family) member 3GDS3669
A7277 PAFA_HUMANPLA2G7, PAFAHPlatelet-activating factor acetylhydrolase precursorGDS3669
A728C ZNT6_HUMANSLC30A6, MST103, ZNT6Zinc transporter 6GDS3669
A7297 PAR14_HUMANPARP14, BAL2Poly [ADP-ribose] polymerase 14GDS3669
A729H P52K_HUMANPRKRIR, DAP4, P52RIPK52 kDa repressor of the inhibitor of the protein kinaseGDS3669
A7331 PDE5A_HUMANPDE5A, PDE5cGMP-specific 3',5'-cyclic phosphodiesteraseGDS3669
A7346 PDK4_HUMANPDK4, PDHK4Pyruvate dehydrogenase [lipoamide kinase] isozyme 4, mitochondrial precursorGDS3669
A7350 PDXK_HUMANPDXK, PKH, PNKPyridoxal kinaseGDS3669
A7369 PGES2_HUMANPTGES2, PGES2Prostaglandin E synthase 2GDS3669
A7372 PGK1_HUMANPGK1, PGKA, MIG10Phosphoglycerate kinase 1GDS3669
A739F CDN2C_HUMANCDKN2C, CDKN6Cyclin-dependent kinase 6 inhibitorGDS3669
A740A NAA38_HUMANLSM8, NAA38N-alpha-acetyltransferase 38, NatC auxiliary subunitGDS3669
A7476 PPBT_HUMANALPLAlkaline phosphatase, tissue-nonspecific isozyme precursorGDS3669
A7479 PPCEL_HUMANPREPLProlyl endopeptidase-likeGDS3669
A7482 PPM1B_HUMANPPM1B, PP2CBProtein phosphatase 1BGDS3669
A7485 PPM1F_HUMANPPM1F, POPX2Ca(2+)/calmodulin-dependent protein kinase phosphataseGDS3669
A7502 PRDX4_HUMANPRDX4Peroxiredoxin 4GDS3669
A7507 PRP16_HUMANDHX38, DDX38, PRP16Pre-mRNA splicing factor ATP-dependent RNA helicase PRP16GDS3669
A750A NCOA7_HUMANNCOA7, ESNA1, ERAP140Nuclear receptor coactivator 7GDS3669
A750F CE028_HUMAN Transmembrane protein C5ORF28GDS3669
A7540 PTGDS_HUMANPTGDS, PDS, PGDS2Prostaglandin-H2 D-isomerase precursorGDS3669
A7542 PTGR1_HUMANPTGR1, LTB4DHProstaglandin reductase 1GDS3669
A7547 PTN23_HUMANPTPN23, HD-PTP, PTP-TD14Protein tyrosine phosphatase HD-PTPGDS3669
A7552 PTRD1_HUMANPTRHD1Similar to ENSANGP00000018456GDS3669
A755H PARP8_HUMANPARP8Poly [ADP-ribose] polymerase 8GDS3669
A756K SPXN4_HUMANSPANXN4, SPANX-N4Sperm protein associated with the nucleus on the X chromosome N4GDS3669
A757F CECR6_HUMANCECR6Cat eye syndrome critical region protein 6GDS3669
A759A NFIC_HUMANNFIC, NFINuclear factor 1 C-typeGDS3669
A760A NFIL3_HUMANNFIL3, E4BP4, IL3BP1Nuclear factor interleukin-3-regulated proteinGDS3669
A764B ABCA1_HUMANABC-1, ABCA1, ABC1ATP-binding cassette, sub-family A (ABC1), member 1GDS3669
A7679 RFNG_HUMANRFNGBeta-1,3-N-acetylglucosaminyltransferase radical fringeGDS3669
A768I THAP2_HUMANTHAP2THAP domain protein 2GDS3669
A7697 RN123_HUMANRNF123, KPC1, FP1477E3 ubiquitin-protein ligase RNF123GDS3669
A7704 RN187_HUMANRNF187E3 ubiquitin-protein ligase RNF187GDS3669
A770F CEP55_HUMANCEP55, URCC6Centrosomal protein of 55 kDaGDS3669
A7715 RNF12_HUMANRNF12, RLIME3 ubiquitin-protein ligase RLIMGDS3669
A7716 RNF13_HUMANRNF13, RZFE3 ubiquitin-protein ligase RNF13GDS3669
A773H PCSK5_HUMANPCSK5, PC5, PC6Proprotein convertase subtilisin/kexin type 5GDS3669
A7794 SERB_HUMANPSPHPhosphoserine phosphataseGDS3669
A7795 SERC_HUMANPSAT1, PSAPhosphoserine aminotransferaseGDS3669
A7803 SGK1_HUMANSGK, SGK1Serine/threonine-protein kinase Sgk1GDS3669
A780H PDE3B_HUMANcGIPDE1, PDE3B, CGIPDE1cGMP-inhibited 3',5'-cyclic phosphodiesterase BGDS3669
A7824 SIK3_HUMANSIK3, QSK, L19Serine/threonine-protein kinase SIK3GDS3669
A783B ABCG1_HUMANABCG1, ABC8, WHT1ATP-binding cassette, sub-family G, member 1GDS3669
A7844 SODM_HUMANSOD2Superoxide dismutase [Mn], mitochondrial precursorGDS3669
A784F CF062_HUMANXTP12Uncharacterized protein C6orf62GDS3669
A7874 ST17B_HUMANSTK17B, DRAK2Serine/threonine protein kinase 17BGDS3669
A787I TISD_HUMANZFP36L2, BRF2, ERF2Butyrate response factor 2GDS3669
A790C ANR24_HUMANANKRD24Ankyrin repeat domain-containing protein 24GDS3669
A792B ACRBP_HUMANACRBP, SP32Acrosin binding proteinGDS3669
A7940 SYVN1_HUMANSYVN1, HRD1, SYNOVIOLIN1E3 ubiquitin-protein ligase SynoviolinGDS3669
A795D PDZ11_HUMANPDZD11, PDZK11, HSPC227PDZ domain containing protein 11GDS3669
A7979 THIM_HUMANACAA2Acetyl-CoA acyltransferase 2GDS3669
A797B ANKH_HUMANANKH, UNQ241/PRO274, UNQ241Progressive ankylosis protein homologGDS3669
A798C ANR50_HUMANANKRD50Ankyrin repeat domain-containing protein 50GDS3669
A798H PG12A_HUMANPLA2G12A, PLA2G12, FKSG38Group XII secretory phospholipase A2 precursorGDS3669
A7992 TLK1_HUMANTLK1Serine/threonine-protein kinase tousled-like 1GDS3669
A799A NR1H3_HUMANNR1H3, LXRANuclear receptor subfamily 1, group H, member 3GDS3669
A8019 TPST2_HUMANTPST2Protein-tyrosine sulfotransferase 2GDS3669
A801C SWAHD_HUMANSOWAHD, ANKRD58Ankyrin repeat domain-containing protein SOWAHDGDS3669
A801F CGRF1_HUMANCGRRF1, CGR19, RNF197Cell growth regulatory with Ring finger domain protein 1GDS3669
A8025 TRI13_HUMANTRIM13, LEU5, RFP2Ret finger protein 2GDS3669
A802G HSF1_HUMANHSF1, HSTF1Heat shock factor protein 1GDS3669
A8034 TRIM8_HUMANTRIM8, GERP, RNF27RING finger protein 27GDS3669
A8047 TRXR1_HUMANTXNRD1, TR, TR1Thioredoxin reductase 1GDS3669
A8077 TXD17_HUMANTXNDC17, TXNL5Thioredoxin domain-containing protein 17GDS3669
A8079 TYDP2_HUMANTDP2, EAP2, TTRAP5'-tyrosyl-DNA phosphodiesteraseGDS3669
A8106 UBE3C_HUMANUBE3CUbiquitin-protein ligase E3CGDS3669
A8137 UBS3B_HUMANUBASH3B, STS1, STS-1Nm23-phosphorylated unknown substrateGDS3669
A8188 VKGC_HUMANGGCX, GCVitamin K-dependent gamma-carboxylaseGDS3669
A8196 WNK1_HUMANWNK1, PRKWNK1, HSN2Serine/threonine-protein kinase WNK1GDS3669
A820G HYLS1_HUMANHYLS1, HLSHydrolethalus syndrome protein 1GDS3669
A821F CI040_HUMAN Hypothetical proteinGDS3669
A8226 ZN363_HUMANRCHY1, ARNIP, CHIMPZinc finger protein 363GDS3669
A823F CI072_HUMAN Conserved hypothetical proteinGDS3669
A829I TM204_HUMANTMEM204, CLP24, UNQ6509/PRO21434Transmembrane protein 204GDS3669
A8387 BIRC5_HUMANBIRC5, API4, IAP4Baculoviral IAP repeat-containing protein 5GDS3669
A838A PDCD4_HUMANPDCD4, H731Programmed cell death 4GDS3669
A841A PER1_HUMANPER1, PER, RIGUIPeriod circadian protein 1GDS3669
A841G ID1_HUMANID1, BHLHB24, IDDNA-binding protein inhibitor ID-1GDS3669
A843G ID3_HUMANID3, 1R21, BHLHB25DNA-binding protein inhibitor ID-3GDS3669
A843H PIM3_HUMANPIM3Serine/threonine-protein kinase pim-3GDS3669
A8448XPEDF_HUMANSERPINF1, PEDF, PIG35Pigment epithelium-derived factor precursorGDS3669
A8449 PHAR1_HUMANPHACTR1, RPEL, RPEL1Phosphatase and actin regulator 1GDS3669
A8451 PHAR3_HUMANPHACTR3, SCAPIN1Phosphatase and actin regulator 3GDS3669
A8478 RGS6_HUMANRGS6, S914Regulator of G-protein signaling 6GDS3669
A848G IEX1_HUMANIER3, IEX1, PRG1Radiation-inducible immediate-early gene IEX-1GDS3669
A8506 SPB9_HUMANSERPINB9, PI9, KE4/cl. 21Cytoplasmic antiproteinase 3GDS3669
A850F CK094_HUMAN Hypothetical protein XP_096472GDS3669
A852F CKLF_HUMANCKLF, CKLF1, HSPC224Chemokine-like factorGDS3669
A852H PK3CG_HUMANPIK3CG, PI3CGPhosphoinositide-3-kinase, catalytic, gamma polypeptideGDS3669
A855I TM2D2_HUMANTM2D2, BLP1TM2 domain-containing protein 2 precursorGDS3669
A858F CL029_HUMAN Uncharacterized protein C12ORF29GDS3669
A859I TM45A_HUMANTMEM45A, DERP7, DNAPTP4Transmembrane protein 45AGDS3669
A861I TM50B_HUMANTMEM50B, UNQ167/PRO193, UNQ167Transmembrane protein 50BGDS3669
A8645 ADAP1_HUMANADAP1, CENTA1Centaurin, alpha 1GDS3669
A864C BOLA3_HUMANBOLA3BOLA-like protein 3GDS3669
A8680 ASTE1_HUMANASTE1, HT001Asteroid homolog 1GDS3669
A868F CLC1A_HUMANCLEC1A, CLEC1, UNQ569/PRO1131C-type lectin domain family 1 member AGDS3669
A8692 CABP5_HUMANCABP5, CABP3Calcium-binding protein 5GDS3669
A869I TMCO2_HUMANTMCO2Transmembrane and coiled-coil domain-containing protein 2GDS3669
A8707 CD180_HUMANLY64, RP105, CD180CD180 antigenGDS3669
A8709 CD83_HUMANCD83CD83 antigen precursorGDS3669
A8715 CK5P2_HUMANCDK5RAP2, CEP215CDK5 regulatory subunit associated protein 2GDS3669
A8718 CNPY3_HUMANCNPY3, CTG4A, ERDA5Protein Canopy homolog 3 precursorGDS3669
A872B CHMP3_HUMANVPS24, CHMP3, NEDFCharged multivesicular body protein 3GDS3669
A872C BTBD7_HUMANBTBD7BTB/POZ domain containing protein 7GDS3669
A872J RB12B_HUMANRBM12BRNA-binding protein 12BGDS3669
A873A PRC2A_HUMANBAT2, PRRC2A, G2Large proline-rich protein BAT2GDS3669
A8741 DAPP1_HUMANDAPP1, BAM32, HSPC066Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositideGDS3669
A874G IKBZ_HUMANNFKBIZ, IKBZ, INAPNF-kappa-B inhibitor zetaGDS3669
A8750 DOC10_HUMANDOCK10, ZIZ3, DRIP2Dedicator of cytokinesis protein 10GDS3669
A876H PLCD4_HUMANPLCD41-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4GDS3669
A8772 FARP1_HUMANFARP1, CDEP, PLEKHC2FERM, RhoGEF and pleckstrin domain-containing protein 1GDS3669
A8776 FBX28_HUMANFBXO28F-box only protein 28GDS3669
A8777 FBX30_HUMANFBXO30, FBX30F-box only protein 30GDS3669
A8788 FGD6_HUMANFGD6, ZFYVE24FYVE, RhoGEF and PH domain containing protein 6GDS3669
A8819 GPSM3_HUMANGPSM3, AGS4, G18G18.1B proteinGDS3669
A881B CLCN3_HUMANCLCN3, CLCN3EChloride channel protein 3GDS3669
A8830 HCLS1_HUMANHCLS1, HS1, P75HS1Hematopoietic lineage cell-specific proteinGDS3669
A8833 HMMR_HUMANHMMR, IHABP, RHAMMHyaluronan mediated motility receptorGDS3669
A885G IL1B_HUMANIL1b, IL1B, IL1F2Interleukin-1 beta precursorGDS3669
A8867 LTBP1_HUMANLTBP1Latent transforming growth factor beta binding protein 1 precursorGDS3669
A886A PTOV1_HUMANPTOV1, ACID2, PP642Prostate tumor overexpressed gene 1 proteinGDS3669
A886F CLTR1_HUMANCYSLTR1, CYSLT1, HG55Cysteinyl leukotriene receptor 1GDS3669
A886I TMM60_HUMANTMEM60, DC32Transmembrane protein 60GDS3669
A8875 MADD_HUMANMADD, DENN, IG20MAP-kinase activating death domain-containing proteinGDS3669
A8913 OTOF_HUMANOTOF, FER1L2OtoferlinGDS3669
A8918 P85A_HUMANPIK3R1, GRB1Phosphatidylinositol 3-kinase regulatory alpha subunitGDS3669
A8945 PP6R3_HUMANPPP6R3, PP6R3, SAPLSerine/threonine-protein phosphatase 6 regulatory subunit 3GDS3669
A8962 PRVA_HUMANPVALBParvalbuminGDS3669
A8976 PTMA_HUMANPTMA, PTMAP7, TMSAProthymosin alphaGDS3669
A9004 RFIP1_HUMANRAB11FIP1, RCPRab11 family-interacting protein 1GDS3669
A901F CNIH1_HUMANCNIH1, CNIH, CNILCornichon homologGDS3669
A9034 RPTOR_HUMANRPTOR, RAPTOR, raptorRegulatory-associated protein of mTORGDS3669
A903A RAVR1_HUMANRAVER1Ribonucleoprotein PTB-binding 1GDS3669
A9044 SELS_HUMANSELS, VIMP, AD-015Selenoprotein SGDS3669
A904A RB15B_HUMANRBM15B, OTT3, HUMAGCGBRNA binding motif protein 15BGDS3669
A9065 SPRE1_HUMANSPRED1Sprouty-related, EVH1 domain-containing protein 1GDS3669
A9089 TBC15_HUMANTBC1D15TBC1 domain family, member 15GDS3669
A908B CPNE2_HUMANCPNE2Copine-2GDS3669
A909G INSI1_HUMANINSIG1Insulin-induced protein 1GDS3669
A909H POGZ_HUMANPOGZ, SUHW5, ZNF280EPOGO transposable element with ZNF domainGDS3669
A910B CPNE4_HUMANCPNE4Copine-4GDS3669
A9121 TMM97_HUMANTMEM97, MAC30Transmembrane protein 97GDS3669
A9124 TNNC2_HUMANTNNC2Troponin C, skeletal muscleGDS3669
A9126 TP8L2_HUMANTNFAIP8L2Tumor necrosis factor, alpha-induced protein 8-like protein 2GDS3669
A9138 UN93B_HUMANUNC93B1, UNC93, UNC93BUNC93 homolog B1GDS3669
A913C CA198_HUMAN Hypothetical protein LOC84886GDS3669
A914I TNF14_HUMANTNFSF14, HVEML, LIGHTTumor necrosis factor ligand superfamily member 14GDS3669
A916I TNFL4_HUMANTNFSF4, TXGP1Tumor necrosis factor ligand superfamily member 4GDS3669
A920K DEN2C_HUMANDENND2CDENN domain-containing protein 2CGDS3669
A9263 CD86_HUMANCD86, CD28LG2T-lymphocyte activation antigen CD86GDS3669
A9271 CLC4A_HUMANCLEC4A, CLECSF6, DCIRDendritic cell immunoreceptorGDS3669
A9273 CLC7A_HUMANUNQ589, CLEC7A, BGRC-type lectin domain family 7 member AGDS3669
A929A RCOR3_HUMANRCOR3REST corepressor 3GDS3669
A929B CYB5_HUMANCYB5A, CYB5Cytochrome B5GDS3669
A930H PPARG_HUMANPPARG, ppar gamma2, NR1C3Peroxisome proliferator activated receptor gammaGDS3669
A931B CYC_HUMANCYCS, CYCCytochrome CGDS3669
A931H PPDPF_HUMANPPDPF, EXPDF, UPF0362Pancreatic progenitor cell differentiation and proliferation factorGDS3669
A934H PPIG_HUMANPPIGPeptidylprolyl cis- trans isomerase GGDS3669
A9353 I27RA_HUMANIL27RA, CRL1, TCCRInterleukin-27 receptor alpha chain precursorGDS3669
A9374 LEPR_HUMANLEPR, DB, OBRLeptin receptor precursorGDS3669
A9377 LGR6_HUMANLGR6, UNQ6427/PRO21331, VTS20631Leucine-rich repeat-containing G protein-coupled receptor 6GDS3669
A9381 LIRA5_HUMANLILRA5, ILT11, LILRB7Leukocyte immunoglobulin-like receptor subfamily A member 5GDS3669
A938A RFX1_HUMANRFX1MHC class II regulatory factor RFX1GDS3669
A940C CC174_HUMANCCDC174, HSPC212Uncharacterized protein C3orf19GDS3669
A9413 NISCH_HUMANNISCH, IRASNischarinGDS3669
A9416 NOTC3_HUMANNOTCH3Neurogenic locus notch homolog protein 3GDS3669
A9426 OLR1_HUMANOLR1, CLEC8A, LOX1Oxidised low density lipoprotein receptor 1GDS3669
A9427 OSCAR_HUMANOSCAR, PIGR3Osteoclast-associated immunoglobulin-like receptorGDS3669
A943F CP072_HUMANPRO0149PRO0149 proteinGDS3669
A945A RNF17_HUMANRNF17, TDRD4RING finger protein 17GDS3669
A9486 STAB1_HUMANSTAB1, FELE-1, FEEL1Stabilin-1 precursorGDS3669
A9491 TACD2_HUMANTACSTD2, GA733-1, M1S1Tumor-associated calcium signal transducer 2 precursorGDS3669
A949I TRAM1_HUMANTRAM1, TRAMTranslocating chain-associated membrane protein 1GDS3669
A9503 TNR21_HUMANTNFRSF21, DR6, UNQ437/PRO868Tumor necrosis factor receptor superfamily member 21 precursorGDS3669
A9513 TRML1_HUMANTREML1, TLT1, UNQ1825/PRO3438Trem-like transcript-1 proteinGDS3669
A9523 VIPR1_HUMANVIPR1Vasoactive intestinal polypeptide receptor 1 precursorGDS3669
A9525 VSIG4_HUMANVSIG4, CRIg, Z39IGV-SET and immunoglobulin domain containing 4GDS3669
A953I TREM1_HUMANTREM1Triggering receptor expressed on monocytes 1GDS3669
A9556 RL27A_HUMANL27a, RPL27A, L27A60S ribosomal protein L27aGDS3669
A9566 RL35A_HUMANRPL35A, GIG3360S ribosomal protein L35aGDS3669
A958I TRI10_HUMANTRIM10, RFB30, RNF9RING finger protein 9GDS3669
A959I TRI11_HUMANTRIM11, RNF92, BIA1Tripartite motif protein 11GDS3669
A960I TRI16_HUMANTRIM16, EBBPTripartite motif protein 16GDS3669
A9613 RM43_HUMANMRPL43, bMRP36a, BMRP36AMitochondrial ribosomal protein L43GDS3669
A961B ETFA_HUMANETFAElectron transfer flavoprotein alpha-subunit, mitochondrial precursorGDS3669
A9626 RO60_HUMANTROVE2, RO60, SSA2TROVE domain family, member 2GDS3669
A963H PRPK_HUMANTP53RK, PRPKp53-related protein kinaseGDS3669
A964C CC132_HUMANCCDC132Coiled-coil domain-containing protein 132GDS3669
A969C CC148_HUMANCCDC148Coiled-coil domain-containing protein 148GDS3669
A9706 DOK3_HUMANDOK3Docking protein 3GDS3669
A9711 ENKUR_HUMANENKUREnkurinGDS3669
A9729 MPP7_HUMANMPP7MAGUK P55 subfamily member 7GDS3669
A972BXFABP4_HUMANFABP4Fatty acid-binding protein 4, adipocyteGDS3669
A973I TRIB1_HUMANTRIB1, C8FW, GIG2Tribbles homolog 1GDS3669
A976G JUNB_HUMANJUNBTranscription factor jun-BGDS3669
A9770 APR_HUMANPMAIP1, NOXAPhorbol-12-myristate-13-acetate-induced protein 1GDS3669
A977I TRIQK_HUMANTRIQKUPF0599 protein C8ORF83GDS3669
A9812 CC038_HUMAN Uncharacterized protein C3ORF38GDS3669
A981C CCD17_HUMANCCDC17Coiled-coil domain-containing protein 17GDS3669
A9826 CD320_HUMANCD320, 8D6A, UNQ198/PRO224CD320 antigenGDS3669
A9828 CD48_HUMANCD48, BCM1, BLAST1B-lymphocyte activation marker BLAST-1 precursorGDS3669
A9831 CD82_HUMANCD82, KAI1, SAR2CD82 antigenGDS3669
A9897 ELMO2_HUMANELMO2, CED12AEngulfment and cell motility protein 2GDS3669
A9923 GMFB_HUMANGMFBGlia maturation factor betaGDS3669
A995B GBRL2_HUMANGABARAPL2, FLC3A, GEF2Ganglioside expression factor 2GDS3669
A9965 ITLN1_HUMANITLN1, INTL, ITLNIntelectin 1GDS3669
A997A SF3A2_HUMANSF3A2, SAP62Splicing factor 3A subunit 2GDS3669
A9980 LSP1_HUMANpp52, LSP1, WP34Lymphocyte-specific protein 1GDS3669
A9992 MELT_HUMANVEPH1, VEPHVentricular-zone expressed PH domain-containing protein homolog 1GDS3669
A9995 MOB1A_HUMANMOBKL1B, MOB1A, MOB4BMob1 proteinGDS3669
A999B GGA3_HUMANGGA3ADP-ribosylation factor binding protein GGA3GDS3669

Compile date 02-09-2018© C/VD project