cvd-logocvd - Molecule ID A9426

geneOLR1, CLEC8A, LOX1
nameOxidised low density lipoprotein receptor 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
OLR1_HUMANP78380ENSG000001733914973Hs.412484602601, 608557

Functions and classifications

GOC:extracellular region, C:integral component of plasma membrane, C:membrane raft, F:carbohydrate binding, F:low-density lipoprotein receptor activity, P:blood circulation, P:blood coagulation, P:cell death, P:inflammatory response, P:leukocyte cell-cell adhesion, P:leukocyte migration, P:lipoprotein metabolic process, P:proteolysis, P:receptor-mediated endocytosis, P:response to hydrogen peroxide, C:integral to plasma membrane
UniProt3D-structure, Alternative splicing, Cell adhesion, Cell membrane, Coiled coil, Complete proteome, Disulfide bond, Glycoprotein, Immunity, Inflammatory response, Lectin, Lipoprotein, Membrane, Palmitate, Polymorphism, Receptor, Reference proteome, Secreted, Signal-anchor, Transmembrane, Transmembrane helix
PADBRCP: receptor

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)0.960<0.05Gene-array19059264
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))1.291<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)1.101<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))0.860<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))1.625<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))0.625<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))1.270<0.05Gene-array25835000
Exp26690514Homo sapiens24bloodwholeCAD (Coronary artery disease (CAD)) 1.74E-02Gene-array26690514
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))1.209<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project