cvd-logocvd - Molecule ID A8668

geneARHGEF10
nameRho guanine nucleotide exchange factor 10
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARHGA_HUMANO15013ENSG000001047289639Hs.98594608136, 608236

Functions and classifications

GOC:cytoskeleton, C:cytosol, C:extracellular region, C:extracellular space, C:plasma membrane, F:arachidonic acid binding, F:calcium ion binding, F:microtubule binding, F:RAGE receptor binding, F:Toll-like receptor 4 binding, F:zinc ion binding, P:activation of cysteine-type endopeptidase activity involved in apoptotic process, P:acute inflammatory response, P:autophagy, P:chemokine production, P:chronic inflammatory response, P:defense response to bacterium, P:defense response to fungus, P:innate immune response, P:leukocyte migration involved in inflammatory response, P:neutrophil aggregation, P:neutrophil chemotaxis, P:positive regulation of cell growth, P:positive regulation of inflammatory response, P:positive regulation of intrinsic apoptotic signaling pathway, P:positive regulation of NF-kappaB transcription factor activity, P:regulation of cytoskeleton organization, P:response to ethanol, P:response to lipopolysaccharide, P:response to zinc ion, P:sequestering of zinc ion, P:wound healing, P:induction of apoptosis
UniProtAlternative splicing, Coiled coil, Complete proteome, Disease mutation, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteome
PADBMOD: modulator, regulator

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseP-valueDetectionPubMed/DOI
Exp26690514Homo sapiens24bloodwholeCAD (Coronary artery disease (CAD))1.48E-02Gene-array26690514

Compile date 02-09-2018© C/VD project