cvd-logocvd - Molecule ID A8663

geneAPOH, B2G1
nameBeta-2-glycoprotein 1 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APOH_HUMANP02749ENSG00000091583350Hs.445358138700

Functions and classifications

GOC:cell surface, C:chylomicron, C:high-density lipoprotein particle, C:very-low-density lipoprotein particle, F:heparin binding, F:lipoprotein lipase activator activity, F:phospholipid binding, P:blood coagulation, intrinsic pathway, P:negative regulation of angiogenesis, P:negative regulation of blood coagulation, P:negative regulation of endothelial cell migration, P:negative regulation of endothelial cell proliferation, P:negative regulation of fibrinolysis, P:negative regulation of myeloid cell apoptotic process, P:negative regulation of smooth muscle cell apoptotic process, P:plasminogen activation, P:positive regulation of lipoprotein lipase activity, P:triglyceride metabolic process, P:triglyceride transport, C:extracellular space, P:regulation of blood coagulation, F:eukaryotic cell surface binding, P:organ regeneration, F:lipid binding, P:blood coagulation, C:cell surface, C:chylomicron, C:high-density lipoprotein particle, C:very-low-density lipoprotein particle, F:heparin binding, F:lipoprotein lipase activator activity, F:phospholipid binding, P:blood coagulation, intrinsic pathway, P:negative regulation of angiogenesis, P:negative regulation of blood coagulation, P:negative regulation of endothelial cell migration, P:negative regulation of endothelial cell proliferation, P:negative regulation of fibrinolysis, P:negative regulation of myeloid cell apoptotic process, P:negative regulation of smooth muscle cell apoptotic process, P:plasminogen activation, P:positive regulation of lipoprotein lipase activity, P:triglyceride metabolic process, P:triglyceride transport, C:extracellular space, P:regulation of blood coagulation, F:eukaryotic cell surface binding, P:organ regeneration, F:lipid binding, P:blood coagulation
UniProt3D-structure, Complete proteome, Direct protein sequencing, Disulfide bond, Glycoprotein, Heparin-binding, Polymorphism, Reference proteome, Repeat, Secreted, Signal, Sushi
PADBUK: unknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21681990aMus musculus6bloodplasmaCAD (APOE-knock out Coronary artery disease (CAD) progression model)1.300<0.05MALDI-TOF/TOF21681990
Exp21681990bMus musculus6bloodplasmaCAD (APOE-knock out Coronary artery disease (CAD) progression model)1.500<0.05MALDI-TOF/TOF21681991
Exp25668619Homo sapiens10urinewholeCAD (Stable Coronary Artery Disease)0.609<0.05nanoLC-ESI-MS/MS25668619

Compile date 02-09-2018© C/VD project