cvd-logocvd - Molecule ID A8019

geneTPST2
nameProtein-tyrosine sulfotransferase 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
TPST2_HUMANO60704ENSG000001282948459Hs.632768603126

Functions and classifications

GOC:endoplasmic reticulum, C:Golgi membrane, C:integral component of membrane, C:membrane, F:protein-tyrosine sulfotransferase activity, P:fusion of sperm to egg plasma membrane, P:peptidyl-tyrosine sulfation, P:prevention of polyspermy, C:integral to membrane, F:transferase activity
UniProt3D-structure, Complete proteome, Disulfide bond, Glycoprotein, Golgi apparatus, Membrane, Reference proteome, Signal-anchor, Transferase, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)0.868<0.05Gene-array19059264
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))1.486<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)1.105<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))0.752<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))0.552<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))2.219<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))0.675<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))1.216<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project