cvd-logocvd - Molecule ID A798C

geneANKRD50
nameAnkyrin repeat domain-containing protein 50
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
ANR50_HUMANQ9ULJ7ENSG0000015145857182Hs.480694

Functions and classifications

GOC:extracellular space, C:membrane attack complex, F:chemokine activity, F:endopeptidase inhibitor activity, P:activation of MAPK activity, P:cellular calcium ion homeostasis, P:chemotaxis, P:complement activation, P:complement activation, alternative pathway, P:complement activation, classical pathway, P:cytolysis, P:G-protein coupled receptor signaling pathway, P:glucose homeostasis, P:in utero embryonic development, P:inflammatory response, P:innate immune response, P:leukocyte migration involved in inflammatory response, P:negative regulation of dopamine secretion, P:negative regulation of endopeptidase activity, P:negative regulation of macrophage chemotaxis, P:negative regulation of norepinephrine secretion, P:positive regulation of angiogenesis, P:positive regulation of chemokine secretion, P:positive regulation of chemotaxis, P:positive regulation vascular endothelial growth factor production, P:regulation of complement activation, C:extracellular region, P:induction of apoptosis, P:positive regulation vascular endothelial growth factor production
UniProtAlternative splicing, ANK repeat, Complete proteome, Direct protein sequencing, Phosphoprotein, Reference proteome, Repeat
PADBUK: unknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)1.091<0.05Gene-array19059264
Exp21173733Homo sapiens10bloodwholeAtherosclerosis (Atherosclerosis familial hypercholesterolemia) 0.0117516Gene-array21173733
Exp21681990dMus musculus6bloodplasmaCAD (APOE-knock out Coronary artery disease (CAD) progression model)0.280<0.05ESI-LTQ(PQD)-Orbitrap21681991
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))1.699<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)1.151<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))1.646<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))1.309<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))1.404<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))1.267<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))0.368<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project