cvd-logocvd - Molecule ID A7668

geneADARB1, hRED1, ADAR2d
nameRNA-specific adenosine deaminase B1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
RED1_HUMANP78563ENSG00000197381104Hs.474018601218

Functions and classifications

GOC:nucleolus, C:nucleoplasm, C:nucleus, F:adenosine deaminase activity, F:double-stranded RNA adenosine deaminase activity, F:double-stranded RNA binding, F:metal ion binding, F:mRNA binding, F:RNA binding, P:adenosine to inosine editing, P:base conversion or substitution editing, P:defense response to virus, P:gene expression, P:innate immune response, P:mRNA modification, P:mRNA processing, P:negative regulation of cell migration, P:negative regulation of cell proliferation, P:negative regulation of protein kinase activity by regulation of protein phosphorylation, P:positive regulation of viral genome replication, P:regulation of cell cycle, P:RNA processing, C:intracellular, C:nucleolus, C:nucleoplasm, C:nucleus, F:adenosine deaminase activity, F:double-stranded RNA adenosine deaminase activity, F:double-stranded RNA binding, F:metal ion binding, F:mRNA binding, F:RNA binding, P:adenosine to inosine editing, P:base conversion or substitution editing, P:defense response to virus, P:gene expression, P:innate immune response, P:mRNA modification, P:mRNA processing, P:negative regulation of cell migration, P:negative regulation of cell proliferation, P:negative regulation of protein kinase activity by regulation of protein phosphorylation, P:positive regulation of viral genome replication, P:regulation of cell cycle, P:RNA processing, C:intracellular
UniProt3D-structure, Alternative splicing, Antiviral defense, Complete proteome, Hydrolase, Immunity, Innate immunity, Metal-binding, mRNA processing, Nucleus, Phosphoprotein, Reference proteome, Repeat, RNA-binding, Zinc
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseP-valueDetectionPubMed/DOI
Exp15769906aHomo sapiens19heartmyocardiumNICM (Pre-LVAD, nonischemic cardiomyopathy)4.77E-07Gene-array15769906

Compile date 02-09-2018© C/VD project