cvd-logocvd - Molecule ID A6914

geneALOX5, LOG5
nameArachidonate 5-lipoxygenase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
LOX5_HUMANP09917ENSG00000012779240Hs.89499152390

Functions and classifications

GOC:cytosol, C:nuclear envelope lumen, C:nuclear matrix, C:nuclear membrane, F:arachidonate 5-lipoxygenase activity, F:iron ion binding, P:arachidonic acid metabolic process, P:leukotriene biosynthetic process, P:leukotriene production involved in inflammatory response, P:lipoxin metabolic process, P:lipoxygenase pathway, C:dendrite, C:sarcolemma, F:lipoxygenase activity, P:acute inflammatory response, P:positive regulation of vasoconstriction, P:response to hyperoxia, P:response to nutrient, P:sensory perception of pain, P:leukotriene metabolic process, C:cytoplasm, C:nucleus, C:cytosol, C:nuclear envelope lumen, C:nuclear matrix, C:nuclear membrane, F:arachidonate 5-lipoxygenase activity, F:iron ion binding, P:arachidonic acid metabolic process, P:leukotriene biosynthetic process, P:leukotriene production involved in inflammatory response, P:lipoxin metabolic process, P:lipoxygenase pathway, C:dendrite, C:sarcolemma, F:lipoxygenase activity, P:acute inflammatory response, P:positive regulation of vasoconstriction, P:response to hyperoxia, P:response to nutrient, P:sensory perception of pain, P:leukotriene metabolic process, C:cytoplasm, C:nucleus
UniProt3D-structure, Alternative splicing, Calcium, Complete proteome, Cytoplasm, Dioxygenase, Direct protein sequencing, Iron, Leukotriene biosynthesis, Membrane, Metal-binding, Nucleus, Oxidoreductase, Phosphoprotein, Polymorphism, Reference proteome
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseP-valueDetectionPubMed/DOI
Exp17106732Homo sapiens12heartendocardiumDCMi (Inflammatory dilated cardiomyopathy (DCMi))1.34E-04Gene-array17106732
Exp19336532cHomo sapiens24bloodmononuclear cellsICM (Ischemic cardiomyopathy (ICM))0.00090218Gene-array19336532

Compile date 02-09-2018© C/VD project