cvd-logocvd - Molecule ID A6552

geneABAT, GABAT
name4-aminobutyrate aminotransferase, mitochondrial precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
GABT_HUMANP80404ENSG0000018304418Hs.336768137150, 613163

Functions and classifications

GOC:4-aminobutyrate transaminase complex, C:mitochondrial matrix, C:neuron projection, F:(S)-3-amino-2-methylpropionate transaminase activity, F:4-aminobutyrate transaminase activity, F:pyridoxal phosphate binding, F:succinate-semialdehyde dehydrogenase binding, P:behavioral response to cocaine, P:copulation, P:gamma-aminobutyric acid catabolic process, P:locomotory behavior, P:negative regulation of blood pressure, P:neurotransmitter catabolic process, P:neurotransmitter secretion, P:response to drug, P:response to ethanol, P:response to hypoxia, P:response to iron ion, P:response to nicotine, P:gamma-aminobutyric acid metabolic process, C:4-aminobutyrate transaminase complex, C:mitochondrial matrix, C:neuron projection, F:(S)-3-amino-2-methylpropionate transaminase activity, F:4-aminobutyrate transaminase activity, F:pyridoxal phosphate binding, F:succinate-semialdehyde dehydrogenase binding, P:behavioral response to cocaine, P:copulation, P:gamma-aminobutyric acid catabolic process, P:locomotory behavior, P:negative regulation of blood pressure, P:neurotransmitter catabolic process, P:neurotransmitter secretion, P:response to drug, P:response to ethanol, P:response to hypoxia, P:response to iron ion, P:response to nicotine, P:gamma-aminobutyric acid metabolic process
UniProtAcetylation, Aminotransferase, Complete proteome, Direct protein sequencing, Disease mutation, Disulfide bond, Mitochondrion, Neurotransmitter degradation, Polymorphism, Pyridoxal phosphate, Reference proteome, Transferase, Transit peptide
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17106732Homo sapiens12heartendocardiumDCMi (Inflammatory dilated cardiomyopathy (DCMi)) 8.88E-04Gene-array17106732
Exp21417265Homo sapiens17heartmyocardiumDCM (Dilated cardiomyopathy)4.9000.00003985LC-MS/MS21417265

Compile date 02-09-2018© C/VD project