cvd-logocvd - Molecule ID A5827

geneASL, LP3236
nameArgininosuccinate lyase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARLY_HUMANP04424ENSG00000126522435Hs.632015207900, 608310

Functions and classifications

GOC:cytoplasm, C:elastic fiber, C:extracellular space, C:proteinaceous extracellular matrix, F:calcium ion binding, F:integrin binding, P:cell-matrix adhesion, P:elastic fiber assembly, P:protein localization to cell surface, P:regulation of cell growth, P:regulation of removal of superoxide radicals, C:membrane, F:transmembrane signaling receptor activity, P:blood coagulation, P:signal transduction
UniProt3D-structure, Acetylation, Alternative splicing, Amino-acid biosynthesis, Arginine biosynthesis, Complete proteome, Disease mutation, Lyase, Polymorphism, Reference proteome, Urea cycle
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)1.062<0.05Gene-array19059264
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))0.864<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)1.089<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))1.417<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))2.005<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))1.302<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))0.556<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))1.000<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project