cvd-logocvd - Molecule ID A5822

geneARG2
nameArginase-2, mitochondrial precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARGI2_HUMANP78540ENSG00000081181384Hs.226007107830

Functions and classifications

GOC:mitochondrial matrix, F:arginase activity, F:metal ion binding, P:arginine metabolic process, P:nitric oxide biosynthetic process, P:striated muscle contraction, P:urea cycle, P:ureteric bud development, P:apoptotic process, P:cellular response to dexamethasone stimulus, P:cellular response to interferon-gamma, P:cellular response to lipopolysaccharide, P:lung development, P:maternal process involved in female pregnancy, P:midgut development, P:negative regulation of nitric-oxide synthase activity, P:negative regulation of striated muscle contraction, P:regulation of L-arginine import, P:regulation of nitric oxide biosynthetic process, P:response to amine stimulus, P:response to amino acid stimulus, P:response to axon injury, P:response to cadmium ion, P:response to drug, P:response to glucose stimulus, P:response to herbicide, P:response to hypoxia, P:response to mercury ion, P:response to selenium ion, P:response to vitamin E, C:mitochondrial matrix, F:arginase activity, F:metal ion binding, P:arginine metabolic process, P:nitric oxide biosynthetic process, P:striated muscle contraction, P:urea cycle, P:ureteric bud development, P:apoptotic process, P:cellular response to dexamethasone stimulus, P:cellular response to interferon-gamma, P:cellular response to lipopolysaccharide, P:lung development, P:maternal process involved in female pregnancy, P:midgut development, P:negative regulation of nitric-oxide synthase activity, P:negative regulation of striated muscle contraction, P:regulation of L-arginine import, P:regulation of nitric oxide biosynthetic process, P:response to amine stimulus, P:response to amino acid stimulus, P:response to axon injury, P:response to cadmium ion, P:response to drug, P:response to glucose stimulus, P:response to herbicide, P:response to hypoxia, P:response to mercury ion, P:response to selenium ion, P:response to vitamin E
UniProt3D-structure, Arginine metabolism, Complete proteome, Hydrolase, Manganese, Metal-binding, Mitochondrion, Polymorphism, Reference proteome, Transit peptide, Urea cycle
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseP-valueDetectionPubMed/DOI
Exp22427379cHomo sapiens17heartleft ventricle biopsiesNDHF (Non-diabetic heart failure (NDHF))0.007474Gene-array22427379

Compile date 02-09-2018© C/VD project