cvd-logocvd - Molecule ID A5819

geneARAF, ARAF1, PKS
nameA-Raf proto-oncogene serine/threonine-protein kinase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARAF_HUMANP10398ENSG00000078061369Hs.446641311010

Functions and classifications

GOC:mitochondrion, F:ATP binding, F:metal ion binding, F:protein serine/threonine kinase activity, F:receptor signaling protein activity, P:negative regulation of apoptotic process, P:positive regulation of peptidyl-serine phosphorylation, P:regulation of proteasomal ubiquitin-dependent protein catabolic process, P:regulation of TOR signaling, F:kinase activity, C:cytosol, P:intracellular signal transduction, C:intracellular, C:mitochondrion, F:ATP binding, F:metal ion binding, F:protein serine/threonine kinase activity, F:receptor signaling protein activity, P:negative regulation of apoptotic process, P:positive regulation of peptidyl-serine phosphorylation, P:regulation of proteasomal ubiquitin-dependent protein catabolic process, P:regulation of TOR signaling, F:kinase activity, C:cytosol, P:intracellular signal transduction, C:intracellular
UniProt3D-structure, Alternative splicing, ATP-binding, Complete proteome, Kinase, Metal-binding, Nucleotide-binding, Phosphoprotein, Polymorphism, Proto-oncogene, Reference proteome, Serine/threonine-protein kinase, Transferase, Zinc, Zinc-finger
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseP-valueDetectionPubMed/DOI
Exp24339868Homo sapiens17heartapex left ventricleDCM (Dilated cardiomyopathy (DCM))5.87E-04Gene-array24339868

Compile date 02-09-2018© C/VD project