cvd-logocvd - Molecule ID A5794

geneAMPD2
nameAMP deaminase 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AMPD2_HUMANQ01433ENSG00000116337271Hs.82927102771

Functions and classifications

GOC:basement membrane, C:extracellular space, C:extracellular vesicular exosome, C:platelet alpha granule lumen, C:protein complex, F:antioxidant activity, F:copper ion binding, F:DNA binding, F:drug binding, F:fatty acid binding, F:pyridoxal phosphate binding, F:toxic substance binding, F:zinc ion binding, P:bile acid and bile salt transport, P:bile acid metabolic process, P:cellular response to starvation, P:hemolysis by symbiont of host erythrocytes, P:lipoprotein metabolic process, P:maintenance of mitochondrion location, P:negative regulation of apoptotic process, P:platelet activation, P:platelet degranulation, P:positive regulation of circadian sleep/wake cycle, non-REM sleep, P:response to mercury ion, P:response to nutrient, P:response to organic substance, P:response to platinum ion, P:sodium-independent organic anion transport, P:transmembrane transport, P:transport, F:cell surface binding, F:toxin binding
UniProtAlternative splicing, Complete proteome, Hydrolase, Metal-binding, Nucleotide metabolism, Phosphoprotein, Polymorphism, Reference proteome, Zinc
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)0.926<0.05Gene-array19059264
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))0.785<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)0.670<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))1.161<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))1.245<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))0.415<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))0.573<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))1.000<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project