cvd-logocvd - Molecule ID A5777

geneALG5, HSPC149
nameDolichyl-phosphate beta-glucosyltransferase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALG5_HUMANQ9Y673ENSG0000012069729880Hs.507769604565

Functions and classifications

GOC:extracellular region, C:plasma membrane, F:antigen binding, P:complement activation, classical pathway, P:Fc-epsilon receptor signaling pathway, P:Fc-gamma receptor signaling pathway involved in phagocytosis, P:innate immune response, C:membrane, C:integral component of membrane, C:integral to membrane
UniProtAlternative splicing, Complete proteome, Endoplasmic reticulum, Glycoprotein, Glycosyltransferase, Membrane, Reference proteome, Signal-anchor, Transferase, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)1.282<0.05Gene-array19059264
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))1.502<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)0.836<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))1.311<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))0.763<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))0.409<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))1.242<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))1.000<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project