cvd-logocvd - Molecule ID A5732

geneADH5, ADHX, FDH
nameAlcohol dehydrogenase class III chi chain
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADHX_HUMANP11766ENSG00000197894128Hs.78989103710

Functions and classifications

GOC:mitochondrion, C:nucleus, F:alcohol dehydrogenase (NAD) activity, F:electron carrier activity, F:fatty acid binding, F:formaldehyde dehydrogenase activity, F:S-(hydroxymethyl)glutathione dehydrogenase activity, F:zinc ion binding, P:aging, P:ethanol catabolic process, P:ethanol oxidation, P:formaldehyde catabolic process, P:peptidyl-cysteine S-nitrosylation, P:positive regulation of blood pressure, P:respiratory system process, P:response to lipopolysaccharide, P:response to nitrosative stress, P:response to redox state, P:retinoid metabolic process, F:oxidoreductase activity, F:metal ion binding, F:nucleotide binding, C:mitochondrion, C:nucleus, F:alcohol dehydrogenase (NAD) activity, F:electron carrier activity, F:fatty acid binding, F:formaldehyde dehydrogenase activity, F:S-(hydroxymethyl)glutathione dehydrogenase activity, F:zinc ion binding, P:aging, P:ethanol catabolic process, P:ethanol oxidation, P:formaldehyde catabolic process, P:peptidyl-cysteine S-nitrosylation, P:positive regulation of blood pressure, P:respiratory system process, P:response to lipopolysaccharide, P:response to nitrosative stress, P:response to redox state, P:retinoid metabolic process, F:oxidoreductase activity, F:metal ion binding, F:nucleotide binding
UniProt3D-structure, Acetylation, Complete proteome, Cytoplasm, Direct protein sequencing, Metal-binding, NAD, Oxidoreductase, Phosphoprotein, Polymorphism, Reference proteome, Zinc
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19336532bHomo sapiens24bloodmononuclear cellsNICM (Non-ischemic dilated cardiomyopathy (NIDCM) ) 0.0160895Gene-array19336532
Exp21417265Homo sapiens17heartmyocardiumDCM (Dilated cardiomyopathy)0.5000.0000181LC-MS/MS21417265

Compile date 02-09-2018© C/VD project