cvd-logocvd - Molecule ID A5701

geneACVR1B, ACVRLK4, ALK4
nameActivin receptor type-1B
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACV1B_HUMANP36896ENSG0000013550391Hs.438918601300

Functions and classifications

GOC:cuticular plate, C:cytosol, C:fascia adherens, C:intracellular membrane-bounded organelle, C:lateral plasma membrane, C:membrane, C:microtubule cytoskeleton, C:spectrin, C:Z disc, F:actin binding, F:calcium ion binding, F:structural constituent of cytoskeleton, P:actin filament capping, P:axon guidance, P:cellular component disassembly involved in execution phase of apoptosis
UniProtAlternative splicing, ATP-binding, Cell membrane, Complete proteome, Glycoprotein, Kinase, Magnesium, Manganese, Membrane, Metal-binding, Nucleotide-binding, Phosphoprotein, Polymorphism, Receptor, Reference proteome, Serine/threonine-protein kinase, Signal, Transferase, Transmembrane, Transmembrane helix, Ubl conjugation
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)1.109<0.05Gene-array19059264
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))1.539<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)0.827<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))1.188<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))1.208<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))0.643<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))0.652<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))1.000<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project