cvd-logocvd - Molecule ID A4555

geneACTA1, ACTA
nameActin, alpha skeletal muscle
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACTS_HUMANP68133ENSG0000014363258Hs.1288102610, 161800, 255310

Functions and classifications

GOC:actin filament, C:cytosol, C:extracellular vesicular exosome, C:stress fiber, C:striated muscle thin filament, F:ADP binding, F:ATP binding, F:myosin binding, F:structural constituent of cytoskeleton, P:cell growth, P:muscle filament sliding, P:response to extracellular stimulus, P:response to lithium ion, P:response to mechanical stimulus, P:response to steroid hormone, P:skeletal muscle fiber adaptation, P:skeletal muscle fiber development, P:skeletal muscle thin filament assembly, C:cytoplasm, C:cytoskeleton, P:response to steroid hormone stimulus, C:actin filament, C:cytosol, C:extracellular vesicular exosome, C:stress fiber, C:striated muscle thin filament, F:ADP binding, F:ATP binding, F:myosin binding, F:structural constituent of cytoskeleton, P:cell growth, P:muscle filament sliding, P:response to extracellular stimulus, P:response to lithium ion, P:response to mechanical stimulus, P:response to steroid hormone, P:skeletal muscle fiber adaptation, P:skeletal muscle fiber development, P:skeletal muscle thin filament assembly, C:cytoplasm, C:cytoskeleton, P:response to steroid hormone stimulus
UniProt3D-structure, Acetylation, ATP-binding, Complete proteome, Cytoplasm, Cytoskeleton, Disease mutation, Methylation, Muscle protein, Nemaline myopathy, Nucleotide-binding, Oxidation, Reference proteome, Phosphoprotein
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21417265Homo sapiens17heartmyocardiumDCM (Dilated cardiomyopathy)2.4002.49E-11LC-MS/MS21417265
Exp27884156Homo sapiens24heart HF (Heart failure (HF)) 1.23E-05RNA sequencing27884156

Compile date 02-09-2018© C/VD project