cvd-logocvd - Molecule ID A4267

geneABCE1, RLI, RNASEL1
nameATP-binding cassette sub-family E member 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABCE1_HUMANP61221ENSG000001641636059Hs.12013601213

Functions and classifications

GOC:mitochondrion, F:ATP binding, F:ATPase activity, F:iron-sulfur cluster binding, F:ribonuclease inhibitor activity, P:ATP catabolic process, P:response to virus, P:RNA catabolic process, P:viral process, F:electron carrier activity, P:virus-host interaction, F:4 iron, 4 sulfur cluster binding, F:metal ion binding, C:mitochondrion, F:ATP binding, F:ATPase activity, F:iron-sulfur cluster binding, F:ribonuclease inhibitor activity, P:ATP catabolic process, P:response to virus, P:RNA catabolic process, P:viral process, F:electron carrier activity, P:virus-host interaction, F:4 iron, 4 sulfur cluster binding, F:metal ion binding
UniProtATP-binding, Chaperone, Complete proteome, Cytoplasm, Host-virus interaction, Mitochondrion, Nucleotide-binding, Polymorphism, Reference proteome, Repeat, 4Fe-4S, Iron, Iron-sulfur, Metal-binding
PADBCHA: chaperone, chaperonin

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)1.128<0.05Gene-array19059264
Exp19336532bHomo sapiens24bloodmononuclear cellsNICM (Non-ischemic dilated cardiomyopathy (NIDCM) ) 0.0066185Gene-array19336532
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))0.816<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)1.138<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))1.163<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))0.729<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))0.535<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))1.630<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))1.000<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project