cvd-logocvd - Molecule ID A4056

geneANAPC5, APC5, PDL-108
nameAnaphase promoting complex subunit 5
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APC5_HUMANQ9UJX4ENSG0000008905351433Hs.7101606948

Functions and classifications

GOC:anaphase-promoting complex, C:cytosol, C:nucleoplasm, F:ubiquitin-protein ligase activity, P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, P:G2/M transition of mitotic cell cycle, P:mitosis, P:mitotic anaphase, P:mitotic spindle assembly checkpoint, P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, P:protein K11-linked ubiquitination, P:cell division, P:mitotic cell cycle spindle assembly checkpoint, C:anaphase-promoting complex, C:cytosol, C:nucleoplasm, F:ubiquitin-protein ligase activity, P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, P:G2/M transition of mitotic cell cycle, P:mitosis, P:mitotic anaphase, P:mitotic spindle assembly checkpoint, P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, P:protein K11-linked ubiquitination, P:cell division, P:mitotic cell cycle spindle assembly checkpoint
UniProtAlternative splicing, Cell cycle, Cell division, Complete proteome, Mitosis, Phosphoprotein, Polymorphism, Reference proteome, Repeat, TPR repeat, Ubl conjugation pathway
PADBCC: cell cycle (turnover, mitosis, meiosis)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseP-valueDetectionPubMed/DOI
Exp17106732Homo sapiens12heartendocardiumDCMi (Inflammatory dilated cardiomyopathy (DCMi))4.66E-06Gene-array17106732
Exp24801707Homo sapiens52blood AMI (Myocardial infarction)0.04464Whole-genome gene expression24801707

Compile date 02-09-2018© C/VD project