cvd-logocvd - Molecule ID A3876

geneADD1, ADDA
nameAlpha adducin
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADDA_HUMANP35611ENSG00000087274118Hs.183706102680

Functions and classifications

GOC:extracellular region, C:plasma membrane, F:antigen binding, P:complement activation, classical pathway, P:Fc-epsilon receptor signaling pathway, P:Fc-gamma receptor signaling pathway involved in phagocytosis, P:innate immune response
UniProtAcetylation, Actin-binding, Alternative splicing, Calmodulin-binding, Cell membrane, Complete proteome, Cytoplasm, Cytoskeleton, Direct protein sequencing, Membrane, Phosphoprotein, Polymorphism, Reference proteome
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)1.464<0.05Gene-array19059264
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))1.819<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)0.357<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))0.357<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))1.246<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))0.574<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))2.307<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))1.000<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project