cvd-logocvd - Molecule ID A373F

geneARL4A, ARL4
nameADP-ribosylation factor-like protein 4
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARL4A_HUMANP40617ENSG0000012264410124Hs.245540604786

Functions and classifications

GOC:endoplasmic reticulum lumen, C:endoplasmic reticulum-Golgi intermediate compartment, C:extracellular region, C:melanosome, C:plasma membrane, C:procollagen-proline 4-dioxygenase complex, F:procollagen-proline 4-dioxygenase activity, F:protein disulfide isomerase activity, F:protein disulfide oxidoreductase activity, P:cell redox homeostasis, P:cellular response to hypoxia, P:extracellular matrix organization, P:glycerol ether metabolic process, P:lipoprotein metabolic process, P:peptidyl-proline hydroxylation to 4-hydroxy-L-proline, P:regulation of intrinsic apoptotic signaling pathway in response to oxidative stress, P:response to endoplasmic reticulum stress, F:isomerase activity, P:oxidation-reduction process, C:endoplasmic reticulum, C:collagen, F:dioxygenase activity, C:cell surface, F:electron carrier activity, P:lipid metabolic process, C:collagen, F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, P:protein folding
UniProtCell membrane, Complete proteome, Cytoplasm, GTP-binding, Lipoprotein, Membrane, Myristate, Nucleotide-binding, Nucleus, Polymorphism, Reference proteome
PADBUK: unknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)0.776<0.05Gene-array19059264
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))0.759<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)1.299<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))1.299<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))1.411<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))0.254<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))0.813<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))1.000<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project