cvd-logocvd - Molecule ID A369F

geneARHGEF19
nameRho guanine nucleotide exchange factor 19
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARHGJ_HUMANQ8IW93ENSG00000142632128272Hs.591532612496

Functions and classifications

GOF:GTPase activator activity, F:Rho guanyl-nucleotide exchange factor activity, P:positive regulation of Rho GTPase activity, P:regulation of actin cytoskeleton organization, P:wound healing, P:regulation of Rho GTPase activity, C:intracellular, F:phospholipid binding, P:regulation of Rho protein signal transduction
UniProtAlternative splicing, Complete proteome, GTPase activation, Guanine-nucleotide releasing factor, Polymorphism, Reference proteome, SH3 domain
PADBMOD: modulator, regulator

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21681990cMus musculus6bloodplasmaCAD (APOE-knock out Coronary artery disease (CAD) progression model)2.300<0.05ESI-LTQ(PQD)-Orbitrap21681991
Exp21681990dMus musculus6bloodplasmaCAD (APOE-knock out Coronary artery disease (CAD) progression model)2.000<0.05ESI-LTQ(PQD)-Orbitrap21681991

Compile date 02-09-2018© C/VD project