cvd-logocvd - Molecule ID A3594

geneALDH1L1, FTHFD
nameAldehyde dehydrogenase 1 family, member L1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AL1L1_HUMANO75891ENSG0000014490810840Hs.434435600249

Functions and classifications

GOC:mitochondrion, F:catalytic activity, F:formyltetrahydrofolate dehydrogenase activity, F:hydroxymethyl-, formyl- and related transferase activity, F:methyltransferase activity, F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, P:10-formyltetrahydrofolate catabolic process, P:biosynthetic process, P:methylation, P:one-carbon metabolic process, F:formyltetrahydrofolate dehydrogenase activity, F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, P:methylation, F:hydroxymethyl-, formyl- and related transferase activity, P:biosynthetic process, C:cytoplasm, F:oxidoreductase activity, C:mitochondrion, F:catalytic activity, F:formyltetrahydrofolate dehydrogenase activity, F:hydroxymethyl-, formyl- and related transferase activity, F:methyltransferase activity, F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, P:10-formyltetrahydrofolate catabolic process, P:biosynthetic process, P:methylation, P:one-carbon metabolic process, F:formyltetrahydrofolate dehydrogenase activity, F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, P:methylation, F:hydroxymethyl-, formyl- and related transferase activity, P:biosynthetic process, C:cytoplasm, F:oxidoreductase activity
UniProt3D-structure, Alternative splicing, Complete proteome, Cytoplasm, NADP, One-carbon metabolism, Oxidoreductase, Phosphopantetheine, Phosphoprotein, Polymorphism, Reference proteome
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseP-valueDetectionPubMed/DOI
Exp17106732Homo sapiens12heartendocardiumDCMi (Inflammatory dilated cardiomyopathy (DCMi))3.30E-04Gene-array17106732

Compile date 02-09-2018© C/VD project